Fitness data for Rv3198c in Mycobacterium tuberculosis H37Rv

Probable ATP-dependent DNA helicase II UvrD2
SEED: ATP-dependent DNA helicase UvrD/PcrA, actinomycete paralog
KEGG: DNA helicase II / ATP-dependent DNA helicase PcrA

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.9)


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group condition fitness t score  
stress 7H9 with Moxifloxacin 0.121 ug/mL -1.8 -1.1 compare
stress 7H9 with Ethionamide 0.1 ug/mL -1.8 -1.2 compare
stress 7H9 with Linezolid 0.44 ug/mL +0.9 +1.2 compare
stress 7H9 with Rifampicin 0.00045 ug/mL +1.0 +1.3 compare
stress 7H9 with Clofazimine 0.072 ug/mL +1.0 +1.4 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +1.0 +1.6 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.0 +1.7 compare
no stress control no stress control +1.0 +1.8 compare
nitrogen source L-Alanine 10 mM (N) +1.1 +2.0 compare
stress 7H9 with Rifampicin 0.00045 ug/mL +1.2 +1.6 compare
stress 7H9 with Rifampicin 0.014 ug/mL +1.2 +1.5 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.3 +2.2 compare
nitrogen source L-Alanine 10 mM (N) +1.3 +2.4 compare
carbon source L-Lactate 10 mM (C) +1.4 +2.3 compare
nitrogen source Glycine 10 mM (N) +1.5 +2.7 compare
stress 7H9 with Rifampicin 0.014 ug/mL +1.5 +2.0 compare
nitrogen source L-Asparagine 10 mM (N) +1.9 +3.5 compare
nitrogen source L-Glutamine 10 mM (N) +1.9 +3.6 compare
nitrogen source L-Glutamic 10 mM (N) +1.9 +3.2 compare
nitrogen source L-Glutamine 10 mM (N) +2.0 +3.7 compare