Fitness data for Rv3062 in Mycobacterium tuberculosis H37Rv

Probable ATP-dependent DNA ligase LigB (polydeoxyribonucleotide synthase [ATP]) (polynucleotide ligase [ATP]) (sealase) (DNA repair protein) (DNA joinase)
SEED: ATP-dependent DNA ligase (EC 6.5.1.1)
KEGG: DNA ligase (ATP)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.6 -1.7 compare
nitrogen source L-Glutamine 10 mM (N) -0.6 -2.0 compare
nitrogen source Glycine 10 mM (N) -0.6 -2.2 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.6 -1.6 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.6 -1.6 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.5 -1.4 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 -1.3 compare
no stress control no stress control -0.5 -1.4 compare
nitrogen source L-Valine 10 mM (N) -0.5 -1.2 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.5 -1.8 compare
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.5 +1.5 compare
stress 7H9 with Pretomanid 0.213 ug/mL +0.5 +2.1 compare
pH pH 4.5 +0.5 +2.0 compare
stress 7H9 with Pretomanid 0.213 ug/mL +0.6 +2.7 compare
stress 7H9 with Sulfamethizole 0.026 mM +0.6 +2.6 compare
stress 7H9 with Sisomicin 0.07 mM +0.6 +2.3 compare
stress 7H9 with Formaldehyde 0.23 mM +0.7 +2.3 compare
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.7 +1.9 compare
stress 7H9 with Dodecyl Sulfate 0.02 vol% +0.7 +3.2 compare
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.8 +1.5 compare