Fitness data for Rv2993c in Mycobacterium tuberculosis H37Rv

Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)
SEED: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) / 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
carbon source D-Lactate 10 mM (C) -1.0 -1.0 compare
nitrogen source L-Glutamine 10 mM (N) -0.6 -1.2 compare
stress 7H9 with Pretomanid 0.213 ug/mL -0.6 -0.7 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.5 -0.5 compare
nitrogen source L-Aspartic Acid 10 mM (N) -0.5 -1.1 compare
nitrogen source L-Alanine 10 mM (N) -0.5 -1.2 compare
stress 7H9 with Sulfaquinoxaline 0.097 mM +0.5 +0.9 compare
nitrogen source L-Glutamic 10 mM (N) +0.5 +0.7 compare
carbon source propionate (C) +0.5 +0.9 compare
nitrogen source Glycine 10 mM (N) +0.5 +0.9 compare
stress 7H9 with Sulfamethizole 0.026 mM +0.6 +0.9 compare
stress 7H9 with Meropenem 9.6 ug/mL +0.6 +1.4 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.6 +0.9 compare
stress 7H9 with Pretomanid 0.213 ug/mL +0.7 +2.0 compare
carbon source L-Glutamine (C) +0.8 +2.7 compare
nitrogen source L-Glutamine 10 mM (N) +0.8 +1.7 compare
carbon source Palmitic 100 uM (C) +0.8 +1.8 compare
carbon source Glycerol (C) +1.0 +1.8 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +1.1 +1.2 compare
stress 7H9 with Sulfamethizole 0.026 mM +1.1 +2.2 compare