Fitness data for Rv2671 in Mycobacterium tuberculosis H37Rv

Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase)
SEED: 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) homolog

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Clofazimine 0.45 ug/mL -1.3 -3.9 compare
stress 7H9 with Sulfamethizole 0.026 mM -1.1 -3.4 compare
stress 7H9 with Sulfamethizole 0.026 mM -1.1 -4.4 compare
stress 7H9 with Clofazimine 0.072 ug/mL -0.8 -3.2 compare
stress 7H9 with Clofazimine 0.072 ug/mL -0.8 -2.8 compare
stress 7H9 with Clofazimine 0.45 ug/mL -0.7 -1.6 compare
nitrogen source L-Valine 10 mM (N) -0.6 -2.2 compare
stress 7H9 with Linezolid 0.44 ug/mL -0.6 -1.8 compare
nitrogen source L-Glutamine 10 mM (N) -0.5 -1.5 compare
nitrogen source L-Serine 10 mM (N) -0.5 -1.6 compare
carbon source D-Lactate 10 mM (C) -0.5 -1.4 compare
carbon source L-Lactate 10 mM (C) -0.4 -1.3 compare
nitrogen source L-Valine 10 mM (N) -0.4 -1.1 compare
carbon source Palmitic 100 uM (C) -0.4 -1.0 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.4 +1.4 compare
no stress control no stress control +0.6 +1.6 compare
no stress control no stress control +0.7 +2.2 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.8 +2.2 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.9 +2.8 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +1.1 +4.6 compare