Fitness data for Rv2501c in Mycobacterium tuberculosis H37Rv
Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA1: biotin carboxylase + biotin carboxyl carrier protein (BCCP)
SEED: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
KEGG: acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| stress | 7H9 with Pretomanid 0.213 ug/mL | -0.7 | -2.1 | compare |
| no stress control | no stress control | -0.5 | -2.0 | compare |
| stress | 7H9 with Ethambutol 0.75 ug/mL | -0.5 | -1.8 | compare |
| carbon source | propionate (C) | -0.5 | -1.3 | compare |
| carbon source | propionate (C) | -0.5 | -2.3 | compare |
| stress | 7H9 with Ethionamide 0.1 ug/mL | -0.4 | -0.9 | compare |
| no stress control | no stress control | -0.4 | -1.8 | compare |
| stress | 7H9 with Clarithromycin 0.967 ug/mL | -0.4 | -1.1 | compare |
| carbon source | D-Lactate 10 mM (C) | -0.4 | -1.1 | compare |
| no stress control | no stress control | -0.4 | -1.3 | compare |
| carbon source | butyrate 10 mM (C) | +0.4 | +1.5 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | +0.4 | +1.3 | compare |
| stress | 7H9 with Clarithromycin 0.967 ug/mL | +0.4 | +2.0 | compare |
| stress | 7H9 with Levofloxacin 0.3 ug/mL | +0.5 | +1.2 | compare |
| carbon source | acetate (C) | +0.5 | +2.3 | compare |
| nitrogen source | L-Aspartic Acid 10 mM (N) | +0.5 | +2.7 | compare |
| stress | 7H9 with Ofloxacin 0.8 ug/mL | +0.6 | +1.5 | compare |
| carbon source | butyrate 10 mM (C) | +0.6 | +1.7 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | +0.8 | +2.2 | compare |
| stress | 7H9 with Moxifloxacin 0.121 ug/mL | +1.0 | +2.0 | compare |