Fitness data for Rv2388c in Mycobacterium tuberculosis H37Rv

Probable oxygen-independent coproporphyrinogen III oxidase HemN (coproporphyrinogenase) (coprogen oxidase)
SEED: Hypothetical radical SAM family enzyme in heat shock gene cluster, similarity with CPO of BS HemN-type
KEGG: oxygen-independent coproporphyrinogen III oxidase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.3 -1.3 compare
stress 7H9 with Hygromycin B 0.0095 mM -0.2 -1.3 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 +1.4 compare
nitrogen source L-Asparagine 10 mM (N) +0.2 +1.6 compare
nitrogen source L-Alanine 10 mM (N) +0.2 +1.4 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.2 +1.7 compare
carbon source L-Glutamine (C) +0.3 +1.7 compare
stress 7H9 with Sulfamethizole 0.026 mM +0.3 +1.4 compare
carbon source L-Glutamine (C) +0.3 +1.8 compare
nitrogen source L-Aspartic Acid 10 mM (N) +0.3 +1.3 compare
nitrogen source L-Asparagine 10 mM (N) +0.3 +2.0 compare
nitrogen source L-Alanine 10 mM (N) +0.3 +1.9 compare
nitrogen source Glycine 10 mM (N) +0.3 +1.6 compare
nitrogen source L-Aspartic Acid 10 mM (N) +0.3 +2.0 compare
nitrogen source Glycine 10 mM (N) +0.3 +2.5 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.4 +1.9 compare
stress 7H9 with Rifampicin 0.014 ug/mL +0.4 +2.1 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.5 +2.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +5.6 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +6.2 compare