Fitness data for Rv2382c in Mycobacterium tuberculosis H37Rv

Polyketide synthetase MbtC (polyketide synthase)
SEED: Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)
KEGG: mycobactin polyketide synthetase MbtC

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.7)


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group condition fitness t score  
carbon source Stearic 100 uM (C) -2.4 -1.4 compare
nitrogen source L-Valine 10 mM (N) -2.2 -1.4 compare
nitrogen source L-Alanine 10 mM (N) -1.2 -1.0 compare
stress 7H9 with Clofazimine 0.45 ug/mL -1.1 -0.9 compare
stress 7H9 with Linezolid 0.44 ug/mL -0.9 -0.9 compare
nitrogen source L-Glutamine 10 mM (N) -0.9 -0.5 compare
nitrogen source L-Valine 10 mM (N) -0.8 -0.6 compare
nitrogen source L-Asparagine 10 mM (N) +0.7 +0.8 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.8 +0.7 compare
carbon source L-Asparagine (C) +0.8 +1.4 compare
stress 7H9 with Isoniazid 0.025 ug/mL +0.8 +0.9 compare
no stress control no stress control +0.9 +1.0 compare
carbon source D-Glucose (C) +0.9 +1.5 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +0.9 +1.1 compare
stress 7H9 with Meropenem 9.6 ug/mL +1.0 +1.4 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +1.2 +1.2 compare
no stress control no stress control +1.3 +1.3 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.4 +1.3 compare
stress 7H9 with Ethionamide 0.1 ug/mL +1.6 +1.5 compare
stress 7H9 with Pretomanid 0.213 ug/mL +1.6 +1.3 compare