Fitness data for Rv2176 in Mycobacterium tuberculosis H37Rv

Probable transmembrane serine/threonine-protein kinase L PknL (protein kinase L) (STPK L)
SEED: Probable serine/threonine-protein kinase pknL (EC 2.7.11.1)
KEGG: serine/threonine protein kinase, bacterial

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Ethambutol 0.75 ug/mL -0.7 -2.2 compare
stress 7H9 with nitrite 3 mM; pH 5.5 -0.7 -2.1 compare
stress 7H9 with Hygromycin B 0.0095 mM -0.6 -2.8 compare
nitrogen source L-Glutamic 10 mM (N) -0.5 -2.0 compare
no stress control no stress control -0.5 -2.5 compare
stress 7H9 with Ethambutol 0.75 ug/mL -0.5 -1.4 compare
stress 7H9 with Amikacin di2 ug/mL -0.5 -2.2 compare
stress 7H9 with Thioridazine 0.028 mM -0.5 -1.7 compare
stress 7H9 with Phenazine methosulfate 0.0054 mM -0.5 -1.6 compare
nitrogen source L-Valine 10 mM (N) -0.5 -2.6 compare
pH pH 5.5 -0.5 -1.7 compare
carbon source Palmitic 100 uM (C) +0.4 +2.5 compare
stress 7H9 with Norfloxacin 0.125 mM +0.4 +1.0 compare
carbon source Glycerol (C) +0.4 +2.3 compare
stress 7H9 with Spectinomycin 0.029 mM +0.5 +1.6 compare
pH 7H9 pH 5.5 +0.5 +1.8 compare
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.5 +2.6 compare
no stress control no stress control +0.5 +2.1 compare
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +0.6 +2.0 compare
nitrogen source Ammonium chloride 10mM (N) +0.6 +2.2 compare