Fitness data for Rv1940 in Mycobacterium tuberculosis H37Rv

Probable riboflavin biosynthesis protein RibA1 (GTP cyclohydrolase II)
SEED: 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25)
KEGG: 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.4)


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group condition fitness t score  
stress 7H9 with Ofloxacin 0.8 ug/mL -1.1 -1.2 compare
no stress control no stress control -1.0 -1.4 compare
stress 7H9 with Ofloxacin 0.8 ug/mL -1.0 -1.1 compare
carbon source propionate (C) -0.8 -2.1 compare
stress 7H9 with Hygromycin B 0.0095 mM -0.8 -1.3 compare
no stress control no stress control -0.8 -1.2 compare
stress 7H9 with Pretomanid 0.213 ug/mL -0.6 -1.4 compare
nitrogen source L-Glutamine 10 mM (N) -0.6 -1.7 compare
carbon source Palmitic 100 uM (C) -0.6 -1.7 compare
stress 7H9 with Clofazimine 0.45 ug/mL -0.6 -1.6 compare
stress 7H9 with Meropenem 9.6 ug/mL -0.6 -1.4 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.5 -0.6 compare
stress 7H9 with Streptomycin 0.178 ug/mL -0.5 -1.0 compare
no stress control no stress control -0.4 -1.0 compare
stress 7H9 with Sulfamethizole 0.026 mM -0.4 -1.5 compare
stress 7H9 with Clofazimine 0.072 ug/mL -0.4 -1.2 compare
carbon source heptadecanoic 250 uM (C) -0.4 -1.2 compare
carbon source butyrate 10 mM (C) +0.5 +1.3 compare
carbon source pyruvate (C) +0.5 +1.1 compare
stress 7H9 with Linezolid 0.44 ug/mL +0.5 +1.1 compare