Fitness data for Rv1843c in Mycobacterium tuberculosis H37Rv
Probable inosine-5'-monophosphate dehydrogenase GuaB1(imp dehydrogenase) (IMPDH) (IMPD)
SEED: Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
KEGG: IMP dehydrogenase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| stress | 7H9 with Levofloxacin 0.3 ug/mL | -0.3 | -1.5 | compare |
| stress | 7H9 with para-aminosalicylic 0.086 ug/mL | -0.2 | -1.8 | compare |
| nitrogen source | L-Valine 10 mM (N) | -0.2 | -1.5 | compare |
| no stress control | no stress control | +0.2 | +1.4 | compare |
| stress | 7H9 with Meropenem 9.6 ug/mL | +0.2 | +1.4 | compare |
| nitrogen source | L-Alanine 10 mM (N) | +0.2 | +1.7 | compare |
| carbon source | Glycerol (C) | +0.2 | +1.7 | compare |
| nitrogen source | L-Alanine 10 mM (N) | +0.2 | +2.1 | compare |
| stress | 7H9 with Meropenem 9.6 ug/mL | +0.2 | +1.4 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.3 | +1.5 | compare |
| nitrogen source | L-Serine 10 mM (N) | +0.3 | +2.1 | compare |
| carbon source | Glycerol (C) | +0.3 | +2.4 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | +0.3 | +1.5 | compare |
| stress | 7H9 with Dimethyl Sulfoxide 1 vol% | +0.3 | +2.1 | compare |
| nitrogen source | L-Glutamic 10 mM (N) | +0.3 | +1.6 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | +0.3 | +2.0 | compare |
| stress | 7H9 with Ethionamide 0.1 ug/mL | +0.3 | +1.9 | compare |
| stress | 7H9 with Dimethyl Sulfoxide 1 vol% | +0.4 | +2.5 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | +0.5 | +2.9 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | +0.5 | +3.3 | compare |