Fitness data for Rv1743 in Mycobacterium tuberculosis H37Rv
Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E)
SEED: Serine/threonine-protein kinase PknE (EC 2.7.11.1)
KEGG: serine/threonine protein kinase, bacterial
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.1)
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| group | condition | fitness | t score | |
|---|---|---|---|---|
| nitrogen source | L-Valine 10 mM (N) | -0.3 | -1.8 | compare |
| stress | 7H9 with para-aminosalicylic 0.086 ug/mL | -0.2 | -1.4 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | -0.2 | -1.5 | compare |
| stress | 7H9 with Meropenem 9.6 ug/mL | -0.2 | -1.3 | compare |
| no stress control | no stress control | -0.2 | -1.0 | compare |
| nitrogen source | L-Glutamine 10 mM (N) | -0.2 | -1.2 | compare |
| stress | 7H9 with Isoniazid 0.025 ug/mL | -0.1 | -0.9 | compare |
| carbon source | butyrate 10 mM (C) | -0.1 | -1.1 | compare |
| nitrogen source | L-Asparagine 10 mM (N) | -0.1 | -1.0 | compare |
| carbon source | L-Aspartic Acid (C) | -0.1 | -0.9 | compare |
| carbon source | L-Lactate 10 mM (C) | +0.1 | +0.9 | compare |
| stress | 7H9 with Pretomanid 0.213 ug/mL | +0.1 | +0.9 | compare |
| nitrogen source | L-Valine 10 mM (N) | +0.1 | +0.9 | compare |
| stress | 7H9 with Levofloxacin 0.3 ug/mL | +0.1 | +0.9 | compare |
| stress | 7H9 with Bedaquiline 0.15 ug/mL | +0.1 | +0.9 | compare |
| carbon source | L-Lactate 10 mM (C) | +0.2 | +1.1 | compare |
| carbon source | Palmitic 100 uM (C) | +0.2 | +1.2 | compare |
| no stress control | no stress control | +0.2 | +1.1 | compare |
| nitrogen source | Glycine 10 mM (N) | +0.2 | +1.2 | compare |
| carbon source | D-Glucose (C) | +0.2 | +2.0 | compare |