Fitness data for Rv1145 in Mycobacterium tuberculosis H37Rv

Probable conserved transmembrane transport protein MmpL13a
SEED: Integral membrane protein
KEGG: putative drug exporter of the RND superfamily

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.2)


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group condition fitness t score  
stress 7H9 with Sulfamethizole 0.026 mM -0.6 -2.6 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.4 -2.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 -1.7 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.3 -1.6 compare
nitrogen source L-Valine 10 mM (N) -0.3 -1.3 compare
stress 7H9 with Isoniazid 0.025 ug/mL -0.3 -1.3 compare
nitrogen source L-Alanine 10 mM (N) -0.3 -1.6 compare
no stress control no stress control -0.3 -1.7 compare
stress 7H9 with Sulfaquinoxaline 0.097 mM -0.3 -1.5 compare
stress 7H9 with Hygromycin B 0.0095 mM -0.3 -1.6 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.3 -1.0 compare
no stress control no stress control -0.3 -1.2 compare
stress 7H9 with Levofloxacin 0.3 ug/mL +0.2 +1.1 compare
carbon source Stearic 100 uM (C) +0.2 +1.1 compare
stress 7H9 with Clofazimine 0.072 ug/mL +0.2 +1.0 compare
stress 7H9 with Ofloxacin 0.8 ug/mL +0.3 +1.0 compare
carbon source pyruvate (C) +0.3 +1.5 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.3 +1.6 compare
stress 7H9 with Pretomanid 0.213 ug/mL +0.3 +1.0 compare
stress 7H9 with Bedaquiline 0.15 ug/mL +0.3 +2.3 compare