Fitness data for Rv0939 in Mycobacterium tuberculosis H37Rv

Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase
SEED: Fumarylacetoacetase (EC 3.7.1.2)

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.8)


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group condition fitness t score  
stress 7H9 with Hygromycin B 0.0095 mM -1.4 -1.2 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -0.9 -0.6 compare
carbon source D-Glucose (C) -0.8 -1.2 compare
stress 7H9 with Levofloxacin 0.3 ug/mL -0.8 -0.4 compare
stress 7H9 with Clofazimine 0.072 ug/mL +0.8 +0.8 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.8 +1.1 compare
carbon source L-Asparagine (C) +0.8 +1.6 compare
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.8 +0.9 compare
stress 7H9 with Clarithromycin 0.967 ug/mL +0.9 +0.9 compare
nitrogen source L-Asparagine 10 mM (N) +0.9 +0.7 compare
stress 7H9 with Delamanid 0.236 ug/mL +1.0 +1.0 compare
stress 7H9 with Sulfaquinoxaline 0.097 mM +1.0 +1.2 compare
stress 7H9 with Rifampicin 0.014 ug/mL +1.0 +1.5 compare
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.0 +1.6 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +1.1 compare
stress 7H9 with Ethambutol 0.75 ug/mL +1.1 +1.9 compare
nitrogen source L-Glutamine 10 mM (N) +1.4 +1.3 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.5 +1.7 compare
nitrogen source L-Valine 10 mM (N) +1.5 +1.8 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +1.7 +1.6 compare