Fitness data for Rv0468 in Mycobacterium tuberculosis H37Rv

3-hydroxybutyryl-CoA dehydrogenase FadB2 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD)
SEED: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)
KEGG: 3-hydroxybutyryl-CoA dehydrogenase

Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.5)


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group condition fitness t score  
stress 7H9 with Pretomanid 0.213 ug/mL -0.6 -1.4 compare
stress 7H9 with Sulfamethizole 0.026 mM -0.6 -1.6 compare
stress 7H9 with Ethionamide 0.1 ug/mL -0.6 -0.8 compare
nitrogen source L-Valine 10 mM (N) -0.5 -0.9 compare
stress 7H9 with Clarithromycin 0.967 ug/mL -0.5 -0.9 compare
stress 7H9 with Delamanid 0.236 ug/mL -0.5 -0.9 compare
stress 7H9 with Streptomycin 0.178 ug/mL +0.5 +1.2 compare
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.5 +0.9 compare
stress 7H9 with Linezolid 0.44 ug/mL +0.5 +1.4 compare
stress 7H9 with Ethionamide 0.1 ug/mL +0.5 +0.9 compare
carbon source D-Trehalose 10 mM (C) +0.6 +0.9 compare
stress 7H9 with Rifampicin 0.00045 ug/mL +0.6 +1.5 compare
nitrogen source Glycine 10 mM (N) +0.6 +1.9 compare
carbon source D-Glucose (C) +0.7 +2.0 compare
carbon source butyrate 10 mM (C) +0.7 +2.7 compare
stress 7H9 with Rifampicin 0.014 ug/mL +0.7 +2.0 compare
stress 7H9 with Clofazimine 0.45 ug/mL +0.8 +1.6 compare
stress 7H9 with Meropenem 9.6 ug/mL +1.0 +4.0 compare
stress 7H9 with Isoniazid 0.025 ug/mL +1.1 +2.2 compare
stress 7H9 with Rifampicin 0.00045 ug/mL +1.2 +2.5 compare