Fitness data for Rv0319 in Mycobacterium tuberculosis H37Rv
Probable pyrrolidone-carboxylate peptidase Pcp (5-oxoprolyl-peptidase) (pyroglutamyl-peptidase I) (PGP-I) (pyrase)
SEED: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3)
KEGG: pyroglutamyl-peptidase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.3)
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group | condition | fitness | t score | |
---|---|---|---|---|
stress | 7H9 with Isoniazid 0.025 ug/mL | -0.7 | -2.5 | compare |
stress | 7H9 with Moxifloxacin 0.121 ug/mL | -0.7 | -2.1 | compare |
stress | 7H9 with Levofloxacin 0.3 ug/mL | -0.5 | -1.6 | compare |
stress | 7H9 with Ofloxacin 0.8 ug/mL | -0.5 | -2.0 | compare |
nitrogen source | L-Asparagine 10 mM (N) | -0.5 | -1.2 | compare |
nitrogen source | L-Alanine 10 mM (N) | -0.4 | -1.4 | compare |
stress | 7H9 with Moxifloxacin 0.121 ug/mL | -0.4 | -1.1 | compare |
no stress control | no stress control | -0.3 | -1.0 | compare |
stress | 7H9 with Rifampicin 0.00045 ug/mL | -0.3 | -1.4 | compare |
carbon source | Valeric 10 mM (C) | +0.3 | +1.0 | compare |
carbon source | L-Lactate 10 mM (C) | +0.3 | +0.9 | compare |
carbon source | D-Trehalose 10 mM (C) | +0.4 | +0.8 | compare |
carbon source | Glycerol (C) | +0.4 | +2.1 | compare |
nitrogen source | L-Glutamic 10 mM (N) | +0.4 | +1.3 | compare |
carbon source | D-Lactate 10 mM (C) | +0.4 | +1.1 | compare |
carbon source | L-Aspartic Acid (C) | +0.4 | +2.8 | compare |
carbon source | Stearic 100 uM (C) | +0.5 | +1.6 | compare |
stress | 7H9 with Meropenem 9.6 ug/mL | +0.5 | +2.4 | compare |
carbon source | pyruvate (C) | +0.6 | +2.2 | compare |
stress | 7H9 with Streptomycin 0.178 ug/mL | +0.8 | +1.5 | compare |