Fitness data for Rv0070c in Mycobacterium tuberculosis H37Rv
Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2)
SEED: Serine hydroxymethyltransferase (EC 2.1.2.1)
KEGG: glycine hydroxymethyltransferase
Top 20 experiments with the strongest phenotypes (|fitness| ≥ 0.6)
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group | condition | fitness | t score | |
---|---|---|---|---|
stress | 7H9 with Isoniazid 0.025 ug/mL | -1.2 | -1.2 | compare |
nitrogen source | L-Valine 10 mM (N) | -0.9 | -1.4 | compare |
carbon source | L-Aspartic Acid (C) | -0.8 | -1.1 | compare |
nitrogen source | Glycine 10 mM (N) | -0.7 | -1.2 | compare |
carbon source | acetate (C) | -0.7 | -1.0 | compare |
stress | 7H9 with Ofloxacin 0.8 ug/mL | -0.7 | -1.0 | compare |
nitrogen source | Glycine 10 mM (N) | -0.6 | -1.1 | compare |
stress | 7H9 with Streptomycin 0.178 ug/mL | -0.6 | -1.0 | compare |
nitrogen source | L-Aspartic Acid 10 mM (N) | -0.6 | -1.0 | compare |
stress | 7H9 with para-aminosalicylic 0.086 ug/mL | -0.6 | -1.1 | compare |
carbon source | D-Trehalose 10 mM (C) | +0.6 | +1.0 | compare |
carbon source | Glycerol (C) | +0.6 | +1.0 | compare |
carbon source | casaminos 1 mg/mL (C) | +0.7 | +1.0 | compare |
stress | 7H9 with Clofazimine 0.45 ug/mL | +0.7 | +1.7 | compare |
carbon source | L-Lactate 10 mM (C) | +0.9 | +1.6 | compare |
stress | 7H9 with Sulfaquinoxaline 0.097 mM | +1.0 | +2.2 | compare |
carbon source | L-Lactate 10 mM (C) | +1.1 | +1.4 | compare |
carbon source | D,L-Malic Acid 10 mM (C) | +1.3 | +2.8 | compare |
nitrogen source | L-Serine 10 mM (N) | +1.3 | +1.3 | compare |
nitrogen source | L-Serine 10 mM (N) | +2.3 | +2.3 | compare |