Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3897c and Rv3898c are separated by 12 nucleotidesRv3898c and Rv3899c are separated by 161 nucleotidesRv3899c and Rv3900c overlap by 7 nucleotidesRv3900c and Rv3901c are separated by 56 nucleotides Rv3897c: Rv3897c - Conserved hypothetical protein, at 4,383,008 to 4,383,640 Rv3897c Rv3898c: Rv3898c - Conserved hypothetical protein, at 4,383,653 to 4,383,985 Rv3898c Rv3899c: Rv3899c - Conserved hypothetical protein, at 4,384,147 to 4,385,379 Rv3899c Rv3900c: Rv3900c - Conserved hypothetical alanine rich protein, at 4,385,373 to 4,386,308 Rv3900c Rv3901c: Rv3901c - Possible membrane protein, at 4,386,365 to 4,386,814 Rv3901c
Group Condition Rv3897c Rv3898c Rv3899c Rv3900c Rv3901c
stress 7H9 with nitrite 2.5 mM -2.8 -0.4 -0.2 -0.1 -0.1
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -2.3 +0.1 -0.3 -0.2 -0.0
stress 7H9 with Isoniazid 0.025 ug/mL -2.2 +0.0 -0.0 -0.4 -0.1
nitrogen source L-Valine 10 mM (N) -1.9 -0.4 -0.1 -0.2 +0.0
no stress control no stress control -2.3 -0.2 +0.1 +0.1 -0.1
carbon source oleate 200uM (C) -2.2 -0.2 -0.1 +0.1 -0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -1.5 -0.0 -0.1 -0.7 -0.0
stress 7H9 with methylglyoxal 1.2 mM -2.1 -0.2 -0.1 -0.2 +0.2
stress 7H9 with Ethionamide 0.1 ug/mL -2.2 -0.0 -0.1 -0.2 +0.2
no stress control no stress control -1.9 -0.0 +0.1 -0.0 -0.3
no stress control no stress control -2.2 -0.3 -0.0 +0.2 +0.2
carbon source D,L-Malic Acid 10 mM (C) -1.4 -0.2 -0.0 -0.3 -0.1
stress 7H9 with Isoniazid 0.025 ug/mL -2.0 +0.2 +0.3 -0.3 -0.1
stress 7H9 with Clofazimine 0.45 ug/mL -2.2 +0.2 +0.0 -0.0 +0.0
stress 7H9 with Irgasan 0.065 mM -1.7 -0.1 +0.0 -0.2 +0.0
stress 7H9 with Chloramphenicol 0.01 mM -2.3 +0.1 -0.0 +0.3 +0.1
nitrogen source L-Glutamine 10 mM (N) -1.6 +0.4 +0.0 +0.0 -0.1
stress 7H9 with Clofazimine 0.45 ug/mL -1.6 +0.1 +0.3 +0.2 +0.0
stress 7H9 with Norfloxacin 0.125 mM -1.9 +0.1 +0.3 +0.4 +0.2
stress 7H9 with Rifampicin 0.00045 ug/mL -1.5 +0.2 +0.2 +0.1 +0.1
stress 7H9 with Ofloxacin 0.8 ug/mL -1.7 +0.2 +0.2 +0.7 +0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -1.1 +0.5 +0.3 +0.3 +0.2
stress 7H9 with Norfloxacin 0.125 mM -0.9 +0.2 +0.2 +0.6 +0.1
nitrogen source Urea 10mM (N) +0.9 -0.3 +0.4 -0.5 -0.1
stress 7H9 with nitrite 3 mM; pH 5.5 +1.7 +0.1 -0.2 +0.0 -0.2
stress 7H9 with Erythromycin 0.016 mM +1.2 +0.4 -0.3 +0.1 +0.1
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +1.7 -0.1 +0.2 +0.1 +0.2
no stress control no stress control +2.2 +0.0 +0.0 -0.1 +0.1
stress 7H9 with Erythromycin 0.016 mM +2.1 +0.1 -0.0 -0.0 +0.0
stress 7H9 with Spectinomycin 0.029 mM +2.1 +0.1 -0.0 -0.0 +0.2
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