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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3897c and Rv3898c are separated by 12 nucleotides
Rv3898c and Rv3899c are separated by 161 nucleotides
Rv3899c and Rv3900c overlap by 7 nucleotides
Rv3900c and Rv3901c are separated by 56 nucleotides
Rv3897c: Rv3897c - Conserved hypothetical protein, at 4,383,008 to 4,383,640
Rv3897c
Rv3898c: Rv3898c - Conserved hypothetical protein, at 4,383,653 to 4,383,985
Rv3898c
Rv3899c: Rv3899c - Conserved hypothetical protein, at 4,384,147 to 4,385,379
Rv3899c
Rv3900c: Rv3900c - Conserved hypothetical alanine rich protein, at 4,385,373 to 4,386,308
Rv3900c
Rv3901c: Rv3901c - Possible membrane protein, at 4,386,365 to 4,386,814
Rv3901c
Group
Condition
Rv3897c
Rv3898c
Rv3899c
Rv3900c
Rv3901c
stress
7H9 with nitrite 2.5 mM
-2.8
-0.4
-0.2
-0.1
-0.1
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
-2.3
+0.1
-0.3
-0.2
-0.0
stress
7H9 with Isoniazid 0.025 ug/mL
-2.2
+0.0
-0.0
-0.4
-0.1
nitrogen source
L-Valine 10 mM (N)
-1.9
-0.4
-0.1
-0.2
+0.0
no stress control
no stress control
-2.3
-0.2
+0.1
+0.1
-0.1
carbon source
oleate 200uM (C)
-2.2
-0.2
-0.1
+0.1
-0.1
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-1.5
-0.0
-0.1
-0.7
-0.0
stress
7H9 with methylglyoxal 1.2 mM
-2.1
-0.2
-0.1
-0.2
+0.2
stress
7H9 with Ethionamide 0.1 ug/mL
-2.2
-0.0
-0.1
-0.2
+0.2
no stress control
no stress control
-1.9
-0.0
+0.1
-0.0
-0.3
no stress control
no stress control
-2.2
-0.3
-0.0
+0.2
+0.2
carbon source
D,L-Malic Acid 10 mM (C)
-1.4
-0.2
-0.0
-0.3
-0.1
stress
7H9 with Isoniazid 0.025 ug/mL
-2.0
+0.2
+0.3
-0.3
-0.1
stress
7H9 with Clofazimine 0.45 ug/mL
-2.2
+0.2
+0.0
-0.0
+0.0
stress
7H9 with Irgasan 0.065 mM
-1.7
-0.1
+0.0
-0.2
+0.0
stress
7H9 with Chloramphenicol 0.01 mM
-2.3
+0.1
-0.0
+0.3
+0.1
nitrogen source
L-Glutamine 10 mM (N)
-1.6
+0.4
+0.0
+0.0
-0.1
stress
7H9 with Clofazimine 0.45 ug/mL
-1.6
+0.1
+0.3
+0.2
+0.0
stress
7H9 with Norfloxacin 0.125 mM
-1.9
+0.1
+0.3
+0.4
+0.2
stress
7H9 with Rifampicin 0.00045 ug/mL
-1.5
+0.2
+0.2
+0.1
+0.1
stress
7H9 with Ofloxacin 0.8 ug/mL
-1.7
+0.2
+0.2
+0.7
+0.1
stress
7H9 with Moxifloxacin 0.121 ug/mL
-1.1
+0.5
+0.3
+0.3
+0.2
stress
7H9 with Norfloxacin 0.125 mM
-0.9
+0.2
+0.2
+0.6
+0.1
nitrogen source
Urea 10mM (N)
+0.9
-0.3
+0.4
-0.5
-0.1
stress
7H9 with nitrite 3 mM; pH 5.5
+1.7
+0.1
-0.2
+0.0
-0.2
stress
7H9 with Erythromycin 0.016 mM
+1.2
+0.4
-0.3
+0.1
+0.1
stress
7H9 with Ciprofloxacin Hydrochloride 0.0012 mM
+1.7
-0.1
+0.2
+0.1
+0.2
no stress control
no stress control
+2.2
+0.0
+0.0
-0.1
+0.1
stress
7H9 with Erythromycin 0.016 mM
+2.1
+0.1
-0.0
-0.0
+0.0
stress
7H9 with Spectinomycin 0.029 mM
+2.1
+0.1
-0.0
-0.0
+0.2
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