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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3870 and Rv3871 are separated by 102 nucleotides
Rv3871 and Rv3872 are separated by 142 nucleotides
Rv3872 and Rv3873 are separated by 30 nucleotides
Rv3873 and Rv3874 are separated by 92 nucleotides
Rv3870: Rv3870 - ESX conserved component EccCa1. ESX-1 type VII secretion system protein. Possible transmembrane protein., at 4,346,481 to 4,348,724
Rv3870
Rv3871: Rv3871 - ESX conserved component EccCb1. ESX-1 type VII secretion system protein., at 4,348,827 to 4,350,602
Rv3871
Rv3872: Rv3872 - PE family-related protein PE35, at 4,350,745 to 4,351,044
Rv3872
Rv3873: Rv3873 - PPE family protein PPE68, at 4,351,075 to 4,352,181
Rv3873
Rv3874: Rv3874 - 10 kDa culture filtrate antigen EsxB (LHP) (CFP10), at 4,352,274 to 4,352,576
Rv3874
Group
Condition
Rv3870
Rv3871
Rv3872
Rv3873
Rv3874
stress
7H9 with Ramoplanin 0.009 mM
+0.0
-0.0
-0.6
-0.2
-2.4
stress
7H9 with Ethionamide 0.1 ug/mL
-0.1
+0.1
+0.1
-0.1
-2.6
carbon source
D-Trehalose 10 mM (C)
+0.1
+0.1
+0.1
+0.1
-2.4
stress
7H9 with Formaldehyde 0.23 mM
+0.0
-0.0
-0.2
-0.1
-1.5
carbon source
acetate (C)
-0.1
-0.0
-0.3
+0.3
-1.5
carbon source
oleate 200uM (C)
+0.0
-0.1
+0.3
-0.2
-1.5
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-0.2
-0.1
-0.4
+0.4
-1.2
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
-0.2
+0.2
+0.0
+0.3
-1.7
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
+0.2
+0.1
-0.5
+0.0
-1.2
carbon source
D,L-Malic Acid 10 mM (C)
+0.2
+0.1
-0.3
+0.2
-1.5
pH
pH 4.5
+0.0
+0.2
-0.3
+0.2
-1.1
nitrogen source
Urea 10mM (N)
+0.1
+0.1
+0.4
+0.0
-1.6
nitrogen source
Ammonium chloride 10mM (N)
-0.1
+0.0
+0.8
+0.0
-1.7
stress
7H9 with Tetrazolium violet 0.065 mM
+0.1
-0.0
+0.2
+0.2
-1.2
pH
7H9 pH 5.5
-0.0
-0.2
+0.8
+0.0
-0.7
stress
7H9 with Delamanid 0.236 ug/mL
-0.1
-0.1
-0.6
-0.2
+0.9
stress
7H9 with Lomefloxacin 0.0035 mM
+0.1
+0.3
+0.2
+0.4
-1.1
nitrogen source
Ammonium chloride 10mM (N)
-0.2
+0.1
+0.8
+0.1
-0.6
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.2
+0.1
+0.7
-0.6
+0.2
stress
7H9 with Irgasan 0.065 mM
-0.1
-0.2
-0.3
-0.0
+1.4
stress
7H9 with Lomefloxacin 0.0035 mM
+0.1
+0.1
+1.0
+0.3
-0.5
stress
7H9 with Hydrogen peroxide 3.97 mM
+0.1
-0.0
+0.8
-0.2
+0.7
stress
7H9 with Plumbagin 0.01 mM
+0.0
-0.1
+0.3
-0.1
+1.4
stress
7H9 with Menadione 0.005 mM
+0.0
+0.1
-0.2
+0.0
+1.6
nitrogen source
L-Glutamine 10 mM (N)
+0.1
+0.0
+0.2
+0.2
+1.2
stress
7H9 with Tetrazolium violet 0.065 mM
+0.0
+0.1
-0.3
+0.3
+1.8
stress
7H9 with Phenazine methosulfate 0.0054 mM
-0.0
+0.0
+0.2
+0.1
+1.8
stress
7H9 with Cumene hydroperoxide 0.05 mM
+0.0
+0.1
-0.0
+0.1
+2.0
stress
7H9 with Levofloxacin 0.3 ug/mL
-0.1
-0.0
+0.0
+0.0
+2.4
stress
7H9 with Sisomicin 0.07 mM
+0.1
-0.0
+0.6
+0.3
+1.5
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