Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3767c and Rv3768 are separated by 129 nucleotidesRv3768 and Rv3769 are separated by 185 nucleotidesRv3769 and Rv3770c are separated by 312 nucleotidesRv3770c and Rv3770A are separated by 105 nucleotides Rv3767c: Rv3767c - Possible S-adenosylmethionine-dependent methyltransferase, at 4,212,996 to 4,213,940 Rv3767c Rv3768: Rv3768 - Unknown protein, at 4,214,070 to 4,214,429 Rv3768 Rv3769: Rv3769 - Hypothetical protein, at 4,214,615 to 4,214,887 Rv3769 Rv3770c: Rv3770c - Hypothetical leucine rich protein, at 4,215,200 to 4,215,775 Rv3770c Rv3770A: Rv3770A - Probable remnant of a transposase, at 4,215,881 to 4,216,063 Rv3770A
Group Condition Rv3767c Rv3768 Rv3769 Rv3770c Rv3770A
carbon source Palmitic 100 uM (C) -0.1 -1.7 N.D. -0.0 N.D.
stress 7H9 with Sisomicin 0.07 mM +0.2 -1.5 N.D. -0.3 N.D.
carbon source heptadecanoic 250 uM (C) -0.2 -1.1 N.D. -0.1 N.D.
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.3 -1.1 N.D. +0.0 N.D.
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.2 -1.2 N.D. +0.1 N.D.
stress 7H9 with Cloxacillin 0.0386 mM -0.1 -0.9 N.D. -0.2 N.D.
stress 7H9 with Tetrazolium violet 0.065 mM -0.2 -0.6 N.D. -0.2 N.D.
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +0.1 -0.8 N.D. -0.3 N.D.
stress 7H9 with nitrite 2.5 mM +0.0 -1.0 N.D. +0.1 N.D.
no stress control no stress control +0.2 -0.9 N.D. -0.1 N.D.
stress 7H9 with copper (II) chloride 0.08 mM +0.2 -0.9 N.D. -0.1 N.D.
carbon source butyrate 10 mM (C) +0.1 -0.9 N.D. +0.1 N.D.
carbon source butyrate 10 mM (C) +0.2 -0.8 N.D. -0.1 N.D.
stress 7H9 with Meropenem 9.6 ug/mL +0.4 -0.7 N.D. +0.1 N.D.
nitrogen source L-Asparagine 10 mM (N) -0.4 +0.8 N.D. -0.0 N.D.
pH 7H9 pH 5.5 -0.4 +0.7 N.D. +0.2 N.D.
pH 7H9 pH 5.5 -0.2 +0.9 N.D. -0.1 N.D.
stress 7H9 with Antimycin A 0.0186 mM -0.0 +0.9 N.D. -0.3 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 +0.9 N.D. -0.1 N.D.
carbon source cholesterol 100uM (C) -0.2 +0.5 N.D. +0.4 N.D.
stress 7H9 with Amikacin di2 ug/mL -0.2 +1.0 N.D. +0.2 N.D.
stress 7H9 with Linezolid 0.44 ug/mL -0.2 +0.9 N.D. +0.3 N.D.
stress 7H9 with Levofloxacin 0.3 ug/mL +0.0 +0.8 N.D. +0.3 N.D.
nitrogen source L-Serine 10 mM (N) +0.3 +0.9 N.D. -0.0 N.D.
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.2 +1.4 N.D. -0.1 N.D.
nitrogen source L-Glutamine 10 mM (N) +0.3 +0.6 N.D. +0.3 N.D.
nitrogen source L-Glutamic 10 mM (N) +0.0 +1.0 N.D. +0.2 N.D.
no stress control no stress control +0.1 +0.8 N.D. +0.4 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL +0.1 +1.3 N.D. +0.1 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL +0.2 +1.7 N.D. +0.0 N.D.
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