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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3733c and Rv3734c are separated by 13 nucleotides
Rv3734c and Rv3735 are separated by 198 nucleotides
Rv3735 and Rv3736 are separated by 56 nucleotides
Rv3736 and Rv3737 are separated by 3 nucleotides
Rv3733c: Rv3733c - Conserved hypothetical protein, at 4,184,012 to 4,184,512
Rv3733c
Rv3734c: Rv3734c - Putative triacylglycerol synthase (diacylglycerol acyltransferase) Tgs2, at 4,184,526 to 4,185,890
Rv3734c
Rv3735: Rv3735 - Conserved hypothetical protein, at 4,186,089 to 4,186,577
Rv3735
Rv3736: Rv3736 - Transcriptional regulatory protein (probably AraC/XylS-family), at 4,186,634 to 4,187,695
Rv3736
Rv3737: Rv3737 - Probable conserved transmembrane protein, at 4,187,699 to 4,189,288
Rv3737
Group
Condition
Rv3733c
Rv3734c
Rv3735
Rv3736
Rv3737
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-0.3
-0.0
-0.2
-0.2
-0.4
stress
7H9 with Dicloxacillin 0.0069 mM
-0.3
+0.1
+0.1
-0.2
-0.4
carbon source
Palmitic 100 uM (C)
-0.4
+0.1
-0.3
+0.1
+0.0
stress
7H9 with Cetrimonium bromide 0.015 vol%
-0.5
-0.1
+0.3
-0.1
+0.0
stress
7H9 with Antimycin A 0.0186 mM
+0.2
-0.0
+0.2
-0.3
-0.4
stress
7H9 with copper (II) chloride 0.08 mM
-0.2
-0.2
+0.1
-0.2
+0.2
stress
7H9 with copper (II) chloride 0.08 mM
-0.4
-0.2
+0.3
-0.1
+0.5
stress
7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
+0.3
-0.2
+0.1
+0.1
-0.3
stress
7H9 with hypochlorite 0.4 vol%
-0.4
-0.1
+0.1
-0.0
+0.5
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
+0.2
-0.0
-0.2
+0.3
-0.3
stress
7H9 with Dodecyl Sulfate 0.02 vol%
-0.5
-0.2
+0.3
-0.1
+0.5
stress
7H9 with Linezolid 0.3 ug/mL
-0.5
-0.0
+0.3
+0.1
+0.2
stress
7H9 with Zinc Pyrithione 0.00072 mM
+0.3
-0.3
+0.4
-0.1
-0.1
nitrogen source
L-Glutamine 10 mM (N)
-0.4
+0.1
+0.1
-0.0
+0.5
stress
7H9 with Nickel (II) chloride 0.6 mM
-0.3
-0.1
+0.3
-0.1
+0.5
stress
7H9 with Plumbagin 0.01 mM
-0.4
-0.0
+0.1
+0.2
+0.4
stress
7H9 with Chloramphenicol 0.01 mM
+0.1
-0.3
+0.2
-0.0
+0.3
nitrogen source
Ammonium chloride 10mM (N)
+0.5
+0.1
+0.3
+0.1
-0.5
stress
7H9 with Ethionamide 0.1 ug/mL
+0.1
+0.2
+0.2
-0.5
+0.5
stress
7H9 with Ciprofloxacin Hydrochloride 0.001 mM
+0.5
+0.1
+0.1
+0.2
-0.3
stress
7H9 with Zinc Pyrithione 0.00072 mM
-0.2
+0.0
+0.1
+0.2
+0.5
carbon source
propionate (C)
+0.0
+0.1
+0.2
-0.2
+0.6
nitrogen source
Urea 10mM (N)
+0.7
-0.1
+0.1
+0.1
-0.3
stress
7H9 with nitrite 1.5 mM; pH 5.5
+0.6
-0.0
-0.4
-0.1
+0.5
carbon source
cholesterol 100uM (C)
+0.5
+0.2
-0.0
+0.2
-0.2
nitrogen source
L-Serine 10 mM (N)
+0.0
+0.0
+0.3
-0.1
+0.6
nitrogen source
L-Glutamic 10 mM (N)
+0.2
+0.2
+0.1
+0.1
+0.4
pH
pH 5.5
+0.3
+0.1
+0.3
+0.1
+0.3
pH
pH 4.5
+0.7
+1.5
+0.1
-0.1
-0.2
pH
pH 4.5
+0.3
+1.6
+0.5
+0.3
-0.3
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