Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3662c and Rv3663c overlap by 4 nucleotidesRv3663c and Rv3664c overlap by 4 nucleotidesRv3664c and Rv3665c are separated by 55 nucleotidesRv3665c and Rv3666c are separated by 1 nucleotides Rv3662c: Rv3662c - Conserved hypothetical protein, at 4,101,265 to 4,102,035 Rv3662c Rv3663c: Rv3663c - Probable dipeptide-transport ATP-binding protein ABC transporter DppD, at 4,102,032 to 4,103,678 Rv3663c Rv3664c: Rv3664c - Probable dipeptide-transport integral membrane protein ABC transporter DppC, at 4,103,675 to 4,104,475 Rv3664c Rv3665c: Rv3665c - Probable dipeptide-transport integral membrane protein ABC transporter DppB, at 4,104,531 to 4,105,457 Rv3665c Rv3666c: Rv3666c - Probable periplasmic dipeptide-binding lipoprotein DppA, at 4,105,459 to 4,107,084 Rv3666c
Group Condition Rv3662c Rv3663c Rv3664c Rv3665c Rv3666c
carbon source heptadecanoic 250 uM (C) N.D. -1.0 -0.7 N.D. -0.1
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -1.0 -1.2 N.D. +0.7
carbon source acetate (C) N.D. -0.2 -0.5 N.D. -0.7
carbon source heptadecanoic 250 uM (C) N.D. -0.2 -0.4 N.D. -0.5
no stress control no stress control N.D. -0.7 -0.3 N.D. +0.3
stress 7H9 with Delamanid 0.236 ug/mL N.D. -0.6 +0.6 N.D. -0.4
stress 7H9 with Ethionamide 0.1 ug/mL N.D. -0.6 -0.3 N.D. +0.6
carbon source butyrate 10 mM (C) N.D. -0.5 +0.4 N.D. -0.3
carbon source D-Trehalose 10 mM (C) N.D. +0.4 -0.3 N.D. -0.5
stress 7H9 with Clofazimine 0.072 ug/mL N.D. -0.5 -0.4 N.D. +0.6
carbon source Stearic 100 uM (C) N.D. -0.3 +0.5 N.D. -0.3
stress 7H9 with Isoniazid 0.025 ug/mL N.D. +0.7 -1.4 N.D. +0.7
stress 7H9 with para-aminosalicylic 0.086 ug/mL N.D. -0.2 -0.4 N.D. +0.6
no stress control no stress control N.D. -0.6 +0.2 N.D. +0.5
stress 7H9 with Ethionamide 0.1 ug/mL N.D. +0.2 -0.6 N.D. +0.6
no stress control no stress control N.D. -0.4 +0.1 N.D. +0.5
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -0.3 +0.5 N.D. +0.4
stress 7H9 with Clarithromycin 0.967 ug/mL N.D. -0.1 +0.5 N.D. +0.4
nitrogen source Glycine 10 mM (N) N.D. +0.3 +0.5 N.D. +0.2
stress 7H9 with Clofazimine 0.45 ug/mL N.D. +0.9 -0.1 N.D. +0.4
stress 7H9 with Rifampicin 0.014 ug/mL N.D. +0.4 +0.9 N.D. -0.1
stress 7H9 with Meropenem 9.6 ug/mL N.D. +0.5 +0.3 N.D. +0.4
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -0.0 +0.4 N.D. +0.8
stress 7H9 with Meropenem 9.6 ug/mL N.D. +0.6 +0.6 N.D. +0.0
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. +0.1 +0.5 N.D. +0.6
nitrogen source L-Aspartic Acid 10 mM (N) N.D. +0.4 +0.3 N.D. +0.9
stress 7H9 with Linezolid 0.44 ug/mL N.D. +0.6 +0.4 N.D. +0.6
nitrogen source L-Glutamine 10 mM (N) N.D. +0.2 +0.6 N.D. +0.8
nitrogen source L-Valine 10 mM (N) N.D. +0.5 +0.8 N.D. +0.6
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -0.2 +1.1 N.D. +1.0
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