Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3654c and Rv3655c are separated by 8 nucleotidesRv3655c and Rv3656c are separated by 23 nucleotidesRv3656c and Rv3657c are separated by 9 nucleotidesRv3657c and Rv3658c are separated by 23 nucleotides Rv3654c: Rv3654c - Conserved hypothetical protein, at 4,094,660 to 4,094,914 Rv3654c Rv3655c: Rv3655c - Conserved hypothetical protein, at 4,094,923 to 4,095,300 Rv3655c Rv3656c: Rv3656c - Conserved hypothetical protein, at 4,095,324 to 4,095,530 Rv3656c Rv3657c: Rv3657c - Possible conserved alanine rich membrane protein, at 4,095,540 to 4,096,115 Rv3657c Rv3658c: Rv3658c - Probable conserved transmembrane protein, at 4,096,139 to 4,096,939 Rv3658c
Group Condition Rv3654c Rv3655c Rv3656c Rv3657c Rv3658c
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM N.D. -2.5 N.D. -0.5 -0.9
stress 7H9 with Cetrimonium bromide 0.015 vol% N.D. -0.7 N.D. -0.4 -2.1
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM N.D. -1.7 N.D. +0.1 -1.3
nitrogen source Ammonium chloride 10mM (N) N.D. -1.4 N.D. +0.1 -1.4
stress 7H9 with Amikacin di2 ug/mL N.D. -0.8 N.D. +0.4 -2.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% N.D. -0.7 N.D. -0.4 -1.5
stress 7H9 with Tetracycline 0.0058 mM N.D. -0.6 N.D. -0.6 -1.3
stress 7H9 with Hydrogen peroxide 3.97 mM N.D. -0.1 N.D. -0.2 -2.0
no stress control no stress control N.D. -0.5 N.D. -0.5 -1.3
stress 7H9 with Sulfamethizole 0.026 mM N.D. -0.1 N.D. -0.3 -1.9
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM N.D. -1.8 N.D. -0.2 -0.3
stress 7H9 with Sisomicin 0.07 mM N.D. -0.1 N.D. -0.4 -1.7
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM N.D. -0.7 N.D. -0.4 -1.0
stress 7H9 with Amikacin di2 ug/mL N.D. -1.4 N.D. +0.2 -0.8
stress 7H9 with Lomefloxacin 0.0035 mM N.D. -0.2 N.D. +0.1 -1.8
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. -0.9 N.D. -0.7 -0.3
carbon source cholesterol 100uM (C) N.D. -1.1 N.D. +0.2 -0.8
no stress control no stress control N.D. -0.5 N.D. +0.2 -1.2
stress 7H9 with Zinc Pyrithione 0.00072 mM N.D. +0.3 N.D. +0.5 -2.1
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM N.D. -1.4 N.D. -0.3 +0.8
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 N.D. +0.2 N.D. +0.6 -1.6
stress 7H9 with Antimycin A 0.0186 mM N.D. -0.3 N.D. +0.7 -0.9
no stress control no stress control N.D. -1.0 N.D. -0.1 +1.0
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -1.1 N.D. -0.2 +1.2
stress 7H9 with Delamanid 0.236 ug/mL N.D. -1.2 N.D. +0.5 +0.7
stress 7H9 with Clarithromycin 0.967 ug/mL N.D. -1.0 N.D. +0.2 +0.8
stress 7H9 with Econazole nitrate salt 0.0082 mM N.D. +0.9 N.D. +0.2 -1.0
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -0.9 N.D. -0.1 +1.4
no stress control no stress control N.D. -0.6 N.D. -0.2 +1.4
stress 7H9 with copper (II) chloride 0.08 mM N.D. +1.4 N.D. +0.3 +1.4
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