Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3575c and Rv3576 are separated by 189 nucleotidesRv3576 and Rv3577 are separated by 190 nucleotidesRv3577 and Rv3578 are separated by 13 nucleotidesRv3578 and Rv3579c are separated by 41 nucleotides Rv3575c: Rv3575c - Transcriptional regulatory protein (probably LacI-family), at 4,017,089 to 4,018,168 Rv3575c Rv3576: Rv3576 - Possible conserved lipoprotein LppH, at 4,018,358 to 4,019,071 Rv3576 Rv3577: Rv3577 - Conserved hypothetical protein, at 4,019,262 to 4,020,128 Rv3577 Rv3578: Rv3578 - Possible arsenical pump integral membrane protein ArsB2, at 4,020,142 to 4,021,383 Rv3578 Rv3579c: Rv3579c - Possible tRNA/rRNA methyltransferase, at 4,021,425 to 4,022,393 Rv3579c
Group Condition Rv3575c Rv3576 Rv3577 Rv3578 Rv3579c
carbon source butyrate 10 mM (C) -1.5 -0.7 +0.3 -0.0 N.D.
carbon source propionate (C) -1.3 -0.4 -0.1 +0.0 N.D.
carbon source butyrate 10 mM (C) -1.6 +0.3 -0.1 -0.1 N.D.
carbon source Stearic 100 uM (C) -0.7 -0.4 -0.1 -0.1 N.D.
carbon source propionate (C) -1.2 -0.4 +0.1 +0.4 N.D.
stress 7H9 with Meropenem 9.6 ug/mL -0.5 -0.1 -0.3 -0.1 N.D.
stress 7H9 with Clofazimine 0.45 ug/mL -0.1 -0.1 -0.4 -0.3 N.D.
carbon source heptadecanoic 250 uM (C) -0.4 -0.3 +0.1 -0.1 N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.3 -0.4 -0.4 +0.5 N.D.
carbon source L-Glutamine (C) -0.4 -0.4 -0.1 +0.2 N.D.
carbon source Valeric 10 mM (C) -0.5 +0.2 -0.0 -0.4 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL -0.3 -0.6 -0.2 +0.4 N.D.
nitrogen source L-Valine 10 mM (N) -0.0 -0.5 -0.2 +0.2 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 -0.9 -0.2 +0.6 N.D.
carbon source Stearic 100 uM (C) -0.7 +0.1 -0.0 +0.1 N.D.
nitrogen source L-Asparagine 10 mM (N) -0.5 -0.3 +0.1 +0.1 N.D.
carbon source L-Lactate 10 mM (C) -0.3 -0.5 +0.2 +0.1 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL -0.2 -0.4 -0.2 +0.4 N.D.
nitrogen source L-Valine 10 mM (N) -0.2 -0.6 -0.0 +0.4 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL -0.4 +0.1 -0.3 +0.2 N.D.
carbon source casaminos 1 mg/mL (C) +0.2 -0.8 +0.1 +0.3 N.D.
carbon source Glycerol (C) -0.2 -0.4 +0.2 +0.3 N.D.
carbon source Valeric 10 mM (C) -0.3 +0.3 +0.3 -0.4 N.D.
stress 7H9 with Rifampicin 0.014 ug/mL -0.2 -0.2 -0.0 +0.4 N.D.
no stress control no stress control -0.3 -0.2 -0.0 +0.5 N.D.
stress 7H9 with Clarithromycin 0.967 ug/mL -0.2 -0.3 +0.2 +0.3 N.D.
carbon source L-Glutamine (C) -0.4 +0.2 -0.0 +0.3 N.D.
stress 7H9 with Hygromycin B 0.0095 mM -0.2 +0.5 -0.2 +0.0 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL -0.3 -0.0 -0.4 +0.8 N.D.
stress 7H9 with Clofazimine 0.072 ug/mL +0.0 +0.3 +0.4 -0.3 N.D.
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