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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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500 nt
Rv3498c and Rv3499c overlap by 1 nucleotides
Rv3499c and Rv3500c are separated by 19 nucleotides
Rv3500c and Rv3501c are separated by 34 nucleotides
Rv3501c and Rv3502c are separated by 225 nucleotides
Rv3498c: Rv3498c - Mce-family protein Mce4B, at 3,916,946 to 3,917,998
Rv3498c
Rv3499c: Rv3499c - Mce-family protein Mce4A, at 3,917,998 to 3,919,200
Rv3499c
Rv3500c: Rv3500c - Conserved integral membrane protein YrbE4B. Possible ABC transporter., at 3,919,220 to 3,920,062
Rv3500c
Rv3501c: Rv3501c - Conserved integral membrane protein YrbE4A. Possible ABC transporter., at 3,920,097 to 3,920,861
Rv3501c
Rv3502c: Rv3502c - Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenase., at 3,921,087 to 3,922,040
Rv3502c
Group
Condition
Rv3498c
Rv3499c
Rv3500c
Rv3501c
Rv3502c
carbon source
Glycerol (C)
-0.9
-1.1
-1.0
-1.6
-0.4
carbon source
Glycerol (C)
-1.1
-1.4
-1.0
-1.1
-0.4
stress
7H9 with Meropenem 9.6 ug/mL
-1.2
-1.1
-0.9
-1.0
-0.2
nitrogen source
L-Asparagine 10 mM (N)
-1.1
-1.2
-0.9
-0.8
+0.0
stress
7H9 with Meropenem 9.6 ug/mL
-0.7
-0.8
-1.2
-1.0
-0.1
stress
7H9 with Clofazimine 0.45 ug/mL
-0.7
-0.7
-0.8
-0.7
-0.2
carbon source
L-Asparagine (C)
-0.7
-0.7
-0.6
-0.6
-0.3
nitrogen source
L-Aspartic Acid 10 mM (N)
-0.6
-0.7
-0.6
-0.7
-0.2
carbon source
butyrate 10 mM (C)
-0.5
-0.5
-0.7
-0.9
-0.1
stress
7H9 with Clofazimine 0.45 ug/mL
-0.8
-0.6
-0.6
-0.4
-0.2
nitrogen source
Glycine 10 mM (N)
-0.7
-0.7
-0.8
-0.5
+0.1
carbon source
butyrate 10 mM (C)
-0.5
-0.6
-0.6
-0.8
-0.0
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.4
-0.8
-0.7
-0.6
-0.2
nitrogen source
Glycine 10 mM (N)
-0.5
-0.8
-0.8
-0.3
-0.0
no stress control
no stress control
-0.8
-0.5
-0.5
-0.4
-0.2
carbon source
propionate (C)
-0.6
-0.4
-0.5
-0.5
-0.5
nitrogen source
L-Asparagine 10 mM (N)
-0.5
-0.6
-0.7
-0.5
-0.0
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.9
-0.7
-0.6
-0.2
+0.1
no stress control
no stress control
-0.6
-0.5
-0.5
-0.6
-0.1
nitrogen source
L-Glutamine 10 mM (N)
-0.7
-0.7
-0.6
-0.4
+0.1
carbon source
Stearic 100 uM (C)
-0.9
-0.5
-0.6
-0.4
+0.1
carbon source
L-Asparagine (C)
-0.6
-0.6
-0.6
-0.1
-0.3
no stress control
no stress control
-0.7
-0.5
-0.6
-0.4
+0.1
carbon source
Stearic 100 uM (C)
-0.6
-0.5
-0.5
-0.7
+0.3
carbon source
L-Glutamine (C)
-0.4
-0.5
-0.5
-0.2
-0.3
stress
7H9 with Sulfamethizole 0.026 mM
-0.5
-0.3
-0.3
-0.5
-0.3
stress
7H9 with Rifampicin 0.00045 ug/mL
-0.8
-0.3
-0.3
-0.3
-0.2
stress
7H9 with Clofazimine 0.072 ug/mL
-0.7
-0.4
-0.4
-0.2
-0.0
no stress control
no stress control
-0.7
-0.6
-0.5
-0.1
+0.2
nitrogen source
L-Glutamine 10 mM (N)
-0.5
-0.4
-0.5
-0.4
+0.1
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