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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3482c and Rv3483c are separated by 43 nucleotides
Rv3483c and Rv3484 are separated by 265 nucleotides
Rv3484 and Rv3485c are separated by 5 nucleotides
Rv3485c and Rv3486 are separated by 205 nucleotides
Rv3482c: Rv3482c - Probable conserved membrane protein, at 3,901,324 to 3,902,106
Rv3482c
Rv3483c: Rv3483c - Possible exported protein, at 3,902,150 to 3,902,812
Rv3483c
Rv3484: Rv3484 - Possible conserved protein CpsA, at 3,903,078 to 3,904,616
Rv3484
Rv3485c: Rv3485c - Probable short-chain type dehydrogenase/reductase, at 3,904,622 to 3,905,566
Rv3485c
Rv3486: Rv3486 - Conserved protein, at 3,905,772 to 3,906,221
Rv3486
Group
Condition
Rv3482c
Rv3483c
Rv3484
Rv3485c
Rv3486
carbon source
heptadecanoic 250 uM (C)
-0.2
-0.2
-1.4
-0.1
-0.5
stress
7H9 with Ethionamide 0.1 ug/mL
+0.2
-0.2
-1.4
+0.1
-0.6
carbon source
Stearic 100 uM (C)
-0.3
+0.2
-0.9
-0.2
-0.5
carbon source
heptadecanoic 250 uM (C)
-0.1
+0.1
-1.3
-0.2
-0.2
stress
7H9 with Sulfamethizole 0.026 mM
-0.5
-0.8
+0.0
+0.0
-0.2
stress
7H9 with para-aminosalicylic 0.086 ug/mL
-0.1
-0.0
-0.4
-0.4
-0.7
carbon source
Stearic 100 uM (C)
-0.1
+0.0
-0.8
-0.2
-0.5
stress
7H9 with Hygromycin B 0.0095 mM
-0.0
-0.1
-0.4
+0.1
-0.9
carbon source
Valeric 10 mM (C)
-0.1
+0.1
-0.6
-0.0
-0.8
stress
7H9 with Isoniazid 0.025 ug/mL
+0.1
-0.1
-0.8
-0.2
-0.2
nitrogen source
L-Serine 10 mM (N)
+0.1
+0.0
-0.7
+0.0
-0.6
stress
7H9 with Hygromycin B 0.0095 mM
-0.2
+0.0
-0.3
+0.1
-0.8
stress
7H9 with para-aminosalicylic 0.086 ug/mL
+0.0
-0.0
-0.2
+0.1
-0.9
stress
7H9 with Ethionamide 0.1 ug/mL
+0.1
+0.2
-1.2
-0.2
+0.1
no stress control
no stress control
+0.0
+0.2
-0.5
-0.1
-0.5
stress
7H9 with Sulfamethizole 0.026 mM
-0.4
-0.6
+0.1
-0.0
-0.1
carbon source
Valeric 10 mM (C)
+0.1
+0.2
-0.7
+0.1
-0.6
no stress control
no stress control
+0.2
-0.0
-0.5
-0.2
-0.3
stress
7H9 with Sulfaquinoxaline 0.097 mM
+0.2
+0.2
-0.3
+0.0
-0.9
stress
7H9 with Ethambutol 0.75 ug/mL
+0.1
-0.0
+0.4
-0.3
-0.6
nitrogen source
L-Alanine 10 mM (N)
+0.1
+0.2
-0.7
-0.1
+0.2
stress
7H9 with Isoniazid 0.025 ug/mL
+0.3
+0.1
-0.8
+0.0
+0.1
nitrogen source
L-Alanine 10 mM (N)
+0.2
-0.0
-0.7
-0.1
+0.6
stress
7H9 with Clarithromycin 0.967 ug/mL
+0.0
+0.2
+0.5
+0.2
-0.6
stress
7H9 with Rifampicin 0.014 ug/mL
-0.1
-0.1
+0.9
-0.1
-0.2
carbon source
D-Lactate 10 mM (C)
+0.1
-0.3
+0.5
-0.1
+0.3
stress
7H9 with Pretomanid 0.213 ug/mL
+0.2
+0.1
+0.5
+0.2
-0.4
carbon source
D-Trehalose 10 mM (C)
-0.1
-0.2
+0.3
-0.0
+1.1
carbon source
L-Lactate 10 mM (C)
+0.0
+0.0
+0.7
-0.1
+0.4
stress
7H9 with Rifampicin 0.014 ug/mL
-0.0
+0.0
+1.1
+0.2
+0.3
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