Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 236 experiments or choose conditions or try the comparative fitness browser

500 ntRv3436c and Rv3437 are separated by 21 nucleotidesRv3437 and Rv3438 are separated by 9 nucleotidesRv3438 and Rv3439c are separated by 19 nucleotidesRv3439c and Rv3440c are separated by 2 nucleotides Rv3436c: Rv3436c - Probable glucosamine--fructose-6-phosphate aminotransferase [isomerizing] GlmS (hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (glucosamine-6-phosphate synthase), at 3,855,015 to 3,856,889 Rv3436c Rv3437: Rv3437 - Possible conserved transmembrane protein, at 3,856,911 to 3,857,387 Rv3437 Rv3438: Rv3438 - Conserved protein, at 3,857,397 to 3,858,239 Rv3438 Rv3439c: Rv3439c - Conserved hypothetical alanine and proline rich protein, at 3,858,259 to 3,859,662 Rv3439c Rv3440c: Rv3440c - Hypothetical protein, at 3,859,665 to 3,859,976 Rv3440c
Group Condition Rv3436c Rv3437 Rv3438 Rv3439c Rv3440c
nitrogen source Urea 10mM (N) N.D. +0.0 -1.3 -0.2 -0.4
nitrogen source Ammonium chloride 10mM (N) N.D. +0.2 -1.7 +0.0 -0.3
stress 7H9 with Erythromycin 0.016 mM N.D. -0.2 -1.4 +0.1 -0.1
nitrogen source Urea 10mM (N) N.D. +0.3 -1.5 -0.1 -0.3
no stress control no stress control N.D. +0.2 -1.8 -0.1 +0.2
carbon source butyrate 10 mM (C) N.D. +0.3 -1.6 -0.1 -0.0
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 N.D. +0.1 -1.2 +0.2 -0.4
pH pH 4.5 N.D. +0.1 -1.0 -0.1 -0.3
stress 7H9 with Cumene hydroperoxide 0.05 mM N.D. -0.0 -1.2 +0.2 -0.1
nitrogen source L-Valine 10 mM (N) N.D. -0.1 -1.1 -0.0 +0.1
stress 7H9 with 8-hydroxy-nitroquinoline 0.03 mM N.D. +0.4 -1.4 -0.1 +0.0
stress 7H9 with Geneticin G418 0.35 mM N.D. +0.1 -1.2 -0.1 +0.1
stress 7H9 with Irgasan 0.065 mM N.D. -0.1 -1.3 +0.2 +0.1
stress 7H9 with Amikacin di2 ug/mL N.D. -0.1 -1.1 +0.2 +0.0
pH pH 4.5 N.D. -0.2 -0.9 -0.3 +0.4
stress 7H9 with nitrite 5 mM N.D. -0.2 -1.0 +0.2 +0.1
stress 7H9 with Dodecyl Sulfate 0.02 vol% N.D. -0.1 -1.2 +0.3 +0.1
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. +0.3 -1.2 +0.2 -0.0
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. +0.3 -0.6 -0.5 +0.1
no stress control no stress control N.D. +0.2 -1.2 +0.3 +0.0
stress 7H9 with Cetrimonium bromide 0.015 vol% N.D. +0.3 -0.9 +0.1 -0.1
stress 7H9 with Cumene hydroperoxide 0.05 mM N.D. +0.2 -0.9 +0.2 -0.1
stress 7H9 with Menadione 0.005 mM N.D. +0.4 -1.0 +0.3 -0.1
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. +0.4 -0.7 -0.4 +0.3
pH 7H9 pH 5.5 N.D. +0.3 -0.8 +0.4 -0.3
no stress control no stress control N.D. +0.5 -0.6 -0.2 +0.2
no stress control no stress control N.D. +0.2 -0.7 +0.2 +0.3
carbon source cholesterol 100uM (C) N.D. +0.1 +0.9 +0.3 -0.1
stress 7H9 with Clofazimine 0.072 ug/mL N.D. +0.2 +0.8 +0.1 +0.2
carbon source cholesterol 100uM (C) N.D. +0.1 +1.0 +0.2 +0.1
remove
Rv3436c
plot		 remove
Rv3437
plot		 remove
Rv3438		 remove
Rv3439c
plot		 remove
Rv3440c
plot