Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3403c and Rv3404c are separated by 16 nucleotidesRv3404c and Rv3405c are separated by 117 nucleotidesRv3405c and Rv3406 are separated by 61 nucleotidesRv3406 and Rv3407 are separated by 34 nucleotides Rv3403c: Rv3403c - Hypothetical protein, at 3,822,262 to 3,823,863 Rv3403c Rv3404c: Rv3404c - Conserved hypothetical protein, at 3,823,880 to 3,824,584 Rv3404c Rv3405c: Rv3405c - Possible transcriptional regulatory protein, at 3,824,702 to 3,825,268 Rv3405c Rv3406: Rv3406 - Probable dioxygenase, at 3,825,330 to 3,826,217 Rv3406 Rv3407: Rv3407 - Possible antitoxin VapB47, at 3,826,252 to 3,826,551 Rv3407
Group Condition Rv3403c Rv3404c Rv3405c Rv3406 Rv3407
stress 7H9 with Levofloxacin 0.3 ug/mL +0.2 -0.1 -2.9 +0.0 +0.2
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 +0.0 -1.6 -0.2 -0.0
stress 7H9 with Isoniazid 0.025 ug/mL +0.0 +0.1 -1.4 -0.0 -0.1
stress 7H9 with Ethambutol 0.75 ug/mL -0.1 -0.2 -0.6 -0.3 -0.2
no stress control no stress control +0.1 -0.2 -0.6 -0.3 -0.3
no stress control no stress control +0.0 +0.1 -0.7 -0.2 -0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.0 +0.0 -1.1 +0.0 +0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.0 +0.1 -0.7 -0.3 -0.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL +0.1 -0.1 -0.7 -0.2 +0.1
carbon source L-Lactate 10 mM (C) +0.1 +0.1 -0.8 -0.1 -0.3
carbon source Valeric 10 mM (C) +0.1 -0.0 -0.9 +0.1 -0.1
carbon source Stearic 100 uM (C) +0.1 -0.1 -0.9 -0.1 +0.2
stress 7H9 with Delamanid 0.236 ug/mL +0.0 +0.1 -0.7 +0.1 -0.2
carbon source Stearic 100 uM (C) +0.2 +0.0 -0.9 -0.0 +0.2
no stress control no stress control -0.0 +0.0 -0.9 +0.2 +0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.0 +0.0 -0.8 -0.2 +0.5
stress 7H9 with Hygromycin B 0.0095 mM +0.1 -0.0 -0.9 +0.1 +0.4
stress 7H9 with Ofloxacin 0.8 ug/mL +0.1 -0.0 -0.7 -0.0 +0.4
carbon source L-Glutamine (C) +0.2 -0.1 -0.5 +0.1 +0.3
carbon source heptadecanoic 250 uM (C) +0.0 -0.0 -0.6 +0.1 +0.5
stress 7H9 with Pretomanid 0.213 ug/mL +0.1 +0.2 -0.6 +0.0 +0.3
stress 7H9 with Meropenem 9.6 ug/mL +0.1 +0.2 -0.5 -0.1 +0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.0 +0.3 -0.6 -0.1 +0.6
carbon source D-Trehalose 10 mM (C) +0.0 +0.2 +0.7 +0.1 -0.1
carbon source D-Trehalose 10 mM (C) -0.0 -0.0 +1.0 -0.1 +0.0
stress 7H9 with Streptomycin 0.178 ug/mL +0.0 +0.1 +1.0 -0.3 +0.2
carbon source casaminos 1 mg/mL (C) +0.1 +0.1 +0.9 -0.0 -0.0
carbon source D-Glucose (C) +0.1 +0.0 +0.7 +0.1 +0.2
carbon source D,L-Malic Acid 10 mM (C) -0.0 +0.1 +0.9 +0.1 +0.3
stress 7H9 with Streptomycin 0.178 ug/mL +0.3 +0.0 +0.7 +0.0 +0.4
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