Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3403c and Rv3404c are separated by 16 nucleotidesRv3404c and Rv3405c are separated by 117 nucleotidesRv3405c and Rv3406 are separated by 61 nucleotidesRv3406 and Rv3407 are separated by 34 nucleotides Rv3403c: Rv3403c - Hypothetical protein, at 3,822,262 to 3,823,863 Rv3403c Rv3404c: Rv3404c - Conserved hypothetical protein, at 3,823,880 to 3,824,584 Rv3404c Rv3405c: Rv3405c - Possible transcriptional regulatory protein, at 3,824,702 to 3,825,268 Rv3405c Rv3406: Rv3406 - Probable dioxygenase, at 3,825,330 to 3,826,217 Rv3406 Rv3407: Rv3407 - Possible antitoxin VapB47, at 3,826,252 to 3,826,551 Rv3407
Group Condition Rv3403c Rv3404c Rv3405c Rv3406 Rv3407
stress 7H9 with Novobiocin 0.004 mM +0.0 +0.2 -2.7 +0.1 -0.5
stress 7H9 with Levofloxacin 0.3 ug/mL +0.2 -0.1 -2.9 +0.0 +0.3
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 +0.0 -1.6 -0.2 -0.2
stress 7H9 with Novobiocin 0.004 mM +0.2 +0.1 -2.5 +0.1 +0.3
stress 7H9 with nitrate 4 mM +0.0 -0.1 -1.5 +0.2 -0.1
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.0 +0.1 -1.4 -0.1 -0.2
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.0 +0.1 -2.1 +0.1 +0.4
stress 7H9 with Formaldehyde 0.23 mM -0.2 -0.1 -1.2 +0.1 -0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 +0.1 -1.4 -0.1 -0.1
stress 7H9 with Amikacin di2 ug/mL -0.1 +0.1 -1.3 +0.1 -0.1
no stress control no stress control -0.2 +0.1 -1.4 +0.1 +0.3
stress 7H9 with Cloxacillin 0.0386 mM +0.2 +0.1 -1.7 +0.2 +0.2
stress 7H9 with copper (II) chloride 0.08 mM +0.3 -0.0 -1.2 +0.0 -0.2
stress 7H9 with Sutezolid 0.12 ug/mL +0.1 +0.1 -1.0 -0.1 -0.2
stress 7H9 with Lomefloxacin 0.0035 mM +0.1 +0.1 -1.2 -0.2 +0.2
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.0 +0.1 -1.3 +0.1 +0.1
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.0 -0.1 -1.2 +0.2 +0.3
stress 7H9 with Chloramphenicol 0.01 mM +0.2 -0.1 -0.9 +0.1 -0.1
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +0.3 +0.0 -0.9 -0.1 +0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.0 +0.0 -0.8 -0.2 +0.5
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.0 +0.1 -0.7 -0.1 +0.4
stress 7H9 with Hygromycin B 0.0095 mM +0.1 -0.0 -0.9 +0.1 +0.4
stress 7H9 with Lomefloxacin 0.0035 mM +0.3 +0.2 -1.0 -0.1 +0.5
no stress control no stress control +0.0 -0.2 -0.6 +0.3 +0.4
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.2 +0.1 -0.5 -0.2 +0.4
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.0 +0.3 -0.6 -0.1 +0.5
stress 7H9 with copper (II) chloride 0.08 mM +0.3 +0.2 -0.6 +0.3 +0.1
stress 7H9 with Menadione 0.005 mM -0.1 -0.1 +1.1 +0.0 -0.3
stress 7H9 with Streptomycin 0.178 ug/mL +0.0 +0.1 +1.0 -0.3 +0.1
stress 7H9 with Streptomycin 0.178 ug/mL +0.3 +0.0 +0.7 +0.0 +0.5
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