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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3403c and Rv3404c are separated by 16 nucleotides
Rv3404c and Rv3405c are separated by 117 nucleotides
Rv3405c and Rv3406 are separated by 61 nucleotides
Rv3406 and Rv3407 are separated by 34 nucleotides
Rv3403c: Rv3403c - Hypothetical protein, at 3,822,262 to 3,823,863
Rv3403c
Rv3404c: Rv3404c - Conserved hypothetical protein, at 3,823,880 to 3,824,584
Rv3404c
Rv3405c: Rv3405c - Possible transcriptional regulatory protein, at 3,824,702 to 3,825,268
Rv3405c
Rv3406: Rv3406 - Probable dioxygenase, at 3,825,330 to 3,826,217
Rv3406
Rv3407: Rv3407 - Possible antitoxin VapB47, at 3,826,252 to 3,826,551
Rv3407
Group
Condition
Rv3403c
Rv3404c
Rv3405c
Rv3406
Rv3407
stress
7H9 with Novobiocin 0.004 mM
+0.0
+0.2
-2.7
+0.1
-0.5
stress
7H9 with Levofloxacin 0.3 ug/mL
+0.2
-0.1
-2.9
+0.0
+0.3
stress
7H9 with Ethionamide 0.1 ug/mL
-0.1
+0.0
-1.6
-0.2
-0.2
stress
7H9 with Novobiocin 0.004 mM
+0.2
+0.1
-2.5
+0.1
+0.3
stress
7H9 with nitrate 4 mM
+0.0
-0.1
-1.5
+0.2
-0.1
stress
7H9 with 2,4-Dinitrophenol 0.1503 mM
-0.0
+0.1
-1.4
-0.1
-0.2
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
-0.0
+0.1
-2.1
+0.1
+0.4
stress
7H9 with Formaldehyde 0.23 mM
-0.2
-0.1
-1.2
+0.1
-0.1
stress
7H9 with Isoniazid 0.025 ug/mL
-0.0
+0.1
-1.4
-0.1
-0.1
stress
7H9 with Amikacin di2 ug/mL
-0.1
+0.1
-1.3
+0.1
-0.1
no stress control
no stress control
-0.2
+0.1
-1.4
+0.1
+0.3
stress
7H9 with Cloxacillin 0.0386 mM
+0.2
+0.1
-1.7
+0.2
+0.2
stress
7H9 with copper (II) chloride 0.08 mM
+0.3
-0.0
-1.2
+0.0
-0.2
stress
7H9 with Sutezolid 0.12 ug/mL
+0.1
+0.1
-1.0
-0.1
-0.2
stress
7H9 with Lomefloxacin 0.0035 mM
+0.1
+0.1
-1.2
-0.2
+0.2
stress
7H9 with nitrite 1.5 mM; pH 5.5
-0.0
+0.1
-1.3
+0.1
+0.1
stress
7H9 with Phenazine ethosulfate 0.0137 mM
-0.0
-0.1
-1.2
+0.2
+0.3
stress
7H9 with Chloramphenicol 0.01 mM
+0.2
-0.1
-0.9
+0.1
-0.1
stress
7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
+0.3
+0.0
-0.9
-0.1
+0.1
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.0
+0.0
-0.8
-0.2
+0.5
stress
7H9 with 2,4-Dinitrophenol 0.1503 mM
-0.0
+0.1
-0.7
-0.1
+0.4
stress
7H9 with Hygromycin B 0.0095 mM
+0.1
-0.0
-0.9
+0.1
+0.4
stress
7H9 with Lomefloxacin 0.0035 mM
+0.3
+0.2
-1.0
-0.1
+0.5
no stress control
no stress control
+0.0
-0.2
-0.6
+0.3
+0.4
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
+0.2
+0.1
-0.5
-0.2
+0.4
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.0
+0.3
-0.6
-0.1
+0.5
stress
7H9 with copper (II) chloride 0.08 mM
+0.3
+0.2
-0.6
+0.3
+0.1
stress
7H9 with Menadione 0.005 mM
-0.1
-0.1
+1.1
+0.0
-0.3
stress
7H9 with Streptomycin 0.178 ug/mL
+0.0
+0.1
+1.0
-0.3
+0.1
stress
7H9 with Streptomycin 0.178 ug/mL
+0.3
+0.0
+0.7
+0.0
+0.5
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