Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 101 experiments or choose conditions or try the comparative fitness browser

500 ntRv3340 and Rv3341 are separated by 11 nucleotidesRv3341 and Rv3342 overlap by 4 nucleotidesRv3342 and Rv3343c are separated by 8 nucleotidesRv3343c and Rv3344c are separated by 48 nucleotides Rv3340: Rv3340 - Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetylhomoserine (thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase), at 3,726,127 to 3,727,476 Rv3340 Rv3341: Rv3341 - Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA), at 3,727,488 to 3,728,627 Rv3341 Rv3342: Rv3342 - Possible methyltransferase (methylase), at 3,728,624 to 3,729,355 Rv3342 Rv3343c: Rv3343c - PPE family protein PPE54, at 3,729,364 to 3,736,935 Rv3343c Rv3344c: Rv3344c - PE-PGRS family protein PE_PGRS49, at 3,736,984 to 3,738,438 Rv3344c
Group Condition Rv3340 Rv3341 Rv3342 Rv3343c Rv3344c
carbon source L-Asparagine (C) -0.2 N.D. -1.6 -0.1 -0.6
carbon source L-Asparagine (C) -0.2 N.D. -1.1 -0.1 -0.8
carbon source acetate (C) -0.4 N.D. -1.5 -0.1 +0.2
carbon source acetate (C) -0.3 N.D. -1.3 +0.0 +0.2
stress 7H9 with Dimethyl Sulfoxide 1 vol% -0.6 N.D. +0.0 -0.2 -0.5
carbon source L-Aspartic Acid (C) -0.4 N.D. -0.5 -0.0 -0.1
stress 7H9 with Ethambutol 0.75 ug/mL +0.1 N.D. +0.0 -0.3 -0.7
nitrogen source L-Aspartic Acid 10 mM (N) -0.6 N.D. -0.2 +0.0 -0.2
carbon source D-Trehalose 10 mM (C) -0.7 N.D. -0.2 +0.0 -0.2
nitrogen source L-Aspartic Acid 10 mM (N) -0.3 N.D. -0.1 +0.1 -0.5
no stress control no stress control +0.3 N.D. -0.2 -0.1 -0.8
carbon source D-Glucose (C) -0.2 N.D. -0.7 +0.0 +0.1
carbon source Valeric 10 mM (C) -0.9 N.D. +0.2 +0.2 -0.1
stress 7H9 with Bedaquiline 0.15 ug/mL +0.4 N.D. -0.3 -0.1 -0.5
carbon source heptadecanoic 250 uM (C) -0.6 N.D. +0.4 -0.0 -0.3
nitrogen source L-Valine 10 mM (N) +0.1 N.D. -0.4 +0.1 -0.4
carbon source D-Glucose (C) -0.4 N.D. -0.4 +0.1 +0.3
no stress control no stress control -0.1 N.D. +0.4 -0.1 -0.6
no stress control no stress control -0.7 N.D. +0.1 +0.2 +0.2
stress 7H9 with Linezolid 0.44 ug/mL +0.4 N.D. -0.2 +0.2 +0.2
stress 7H9 with Levofloxacin 0.3 ug/mL -0.3 N.D. +0.4 +0.3 +0.5
stress 7H9 with Ofloxacin 0.8 ug/mL -0.2 N.D. +0.1 +0.4 +0.6
stress 7H9 with Clofazimine 0.072 ug/mL +0.6 N.D. +0.2 -0.1 +0.2
stress 7H9 with Streptomycin 0.178 ug/mL -0.1 N.D. +0.2 +0.4 +0.5
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 N.D. +0.2 +0.2 +0.7
stress 7H9 with Isoniazid 0.025 ug/mL -0.1 N.D. +0.6 +0.2 +0.4
no stress control no stress control +0.2 N.D. +0.2 +0.3 +0.6
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 N.D. +0.1 +0.4 +0.9
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.1 N.D. +0.3 +0.3 +0.9
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.2 N.D. +0.7 +0.3 +0.9
remove
Rv3340
plot		 remove
Rv3341
plot		 remove
Rv3342		 remove
Rv3343c
plot		 remove
Rv3344c
plot