Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3303c and Rv3304 are separated by 202 nucleotidesRv3304 and Rv3305c are separated by 18 nucleotidesRv3305c and Rv3306c overlap by 4 nucleotidesRv3306c and Rv3307 are separated by 64 nucleotides Rv3303c: Rv3303c - NAD(P)H quinone reductase LpdA, at 3,689,457 to 3,690,938 Rv3303c Rv3304: Rv3304 - Conserved protein, at 3,691,141 to 3,691,620 Rv3304 Rv3305c: Rv3305c - Possible N-acyl-L-amino acid amidohydrolase AmiA1 (N-acyl-L-amino acid aminohydrolase), at 3,691,639 to 3,692,808 Rv3305c Rv3306c: Rv3306c - Probable amidohydrolase AmiB1 (aminohydrolase), at 3,692,805 to 3,693,989 Rv3306c Rv3307: Rv3307 - Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP), at 3,694,054 to 3,694,860 Rv3307
Group Condition Rv3303c Rv3304 Rv3305c Rv3306c Rv3307
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.0 -0.2 +0.3 -5.1 -0.0
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.3 -0.3 -1.1 -3.2 +0.2
stress 7H9 with Hydrogen peroxide 3.97 mM -0.3 -0.3 -1.3 -2.1 -0.1
carbon source heptadecanoic 250 uM (C) +0.0 -0.4 -0.5 -2.8 +0.1
stress 7H9 with Linezolid 0.44 ug/mL -0.1 -0.2 -1.2 -1.7 -0.3
stress 7H9 with Cloxacillin 0.0386 mM +0.0 -0.1 -0.2 -2.8 -0.1
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.4 -1.4 +0.1 -2.1 +0.1
stress 7H9 with Tetrazolium violet 0.065 mM -0.2 -0.3 -0.2 -2.1 -0.1
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.3 -0.0 +0.3 -2.6 -0.1
stress 7H9 with methylglyoxal 1.2 mM +0.1 -0.4 +0.1 -2.4 -0.1
stress 7H9 with nitrate 4 mM -0.3 -0.5 +0.3 -2.2 -0.1
stress 7H9 with Rifampicin 0.00045 ug/mL -0.0 -0.8 +0.4 -2.2 +0.0
no stress control no stress control -0.7 +0.3 -0.3 -1.3 -0.3
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM -0.1 -0.4 -0.0 -2.0 +0.3
stress 7H9 with Bedaquiline 0.15 ug/mL -1.6 -0.4 +0.4 -0.7 -0.0
carbon source Stearic 100 uM (C) -0.2 +0.6 -0.2 -2.2 -0.1
pH pH 4.5 -0.8 -1.8 +0.8 +0.1 -0.1
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.3 -0.1 +0.8 -1.6 +0.1
stress 7H9 with Hygromycin B 0.0095 mM +0.1 -0.6 +0.9 -1.2 -0.3
pH pH 4.5 -0.8 -1.6 +0.7 +1.1 -0.3
stress 7H9 with copper (II) chloride 0.08 mM -0.0 +0.2 +0.9 -2.1 +0.1
no stress control no stress control -0.6 +0.5 +0.6 -1.2 -0.1
stress 7H9 with nitrite 2.5 mM -0.5 +0.2 +0.8 -1.3 +0.1
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -0.1 -0.7 -0.7 +1.2 -0.3
stress 7H9 with copper (II) chloride 0.08 mM -0.3 -0.1 +1.3 -1.2 -0.1
stress 7H9 with Cetrimonium bromide 0.015 vol% +0.1 +0.5 -1.6 +0.7 +0.2
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.1 -1.5 +0.3 +1.2 -0.2
stress 7H9 with Isoniazid 0.025 ug/mL -0.5 +0.4 -0.4 +1.4 -0.5
stress 7H9 with Sisomicin 0.07 mM +0.3 -0.8 +1.4 -0.6 +0.2
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 +0.8 -0.3 +1.4 -0.5
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