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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3290c and Rv3291c are separated by 50 nucleotides
Rv3291c and Rv3292 are separated by 30 nucleotides
Rv3292 and Rv3293 are separated by 26 nucleotides
Rv3293 and Rv3294c are separated by 99 nucleotides
Rv3290c: Rv3290c - Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase), at 3,670,445 to 3,671,794
Rv3290c
Rv3291c: Rv3291c - Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family), at 3,671,845 to 3,672,297
Rv3291c
Rv3292: Rv3292 - Conserved hypothetical protein, at 3,672,328 to 3,673,575
Rv3292
Rv3293: Rv3293 - Probable piperideine-6-carboxilic acid dehydrogenase Pcd (piperideine-6-carboxylate dehydrogenase), at 3,673,602 to 3,675,086
Rv3293
Rv3294c: Rv3294c - Conserved hypothetical protein, at 3,675,186 to 3,675,995
Rv3294c
Group
Condition
Rv3290c
Rv3291c
Rv3292
Rv3293
Rv3294c
nitrogen source
L-Asparagine 10 mM (N)
-0.3
-0.3
-0.3
-0.1
-0.0
stress
7H9 with para-aminosalicylic 0.086 ug/mL
-0.2
-0.4
-0.2
-0.2
+0.0
stress
7H9 with Isoniazid 0.025 ug/mL
-0.3
-0.4
-0.4
-0.0
+0.1
stress
7H9 with Levofloxacin 0.3 ug/mL
-0.2
-0.1
-0.5
-0.3
+0.3
stress
7H9 with Isoniazid 0.025 ug/mL
-0.4
-0.0
-0.7
-0.2
+0.3
carbon source
L-Lactate 10 mM (C)
-0.2
-1.0
+0.0
+0.3
+0.1
stress
7H9 with Streptomycin 0.178 ug/mL
-0.1
-0.4
-0.4
-0.1
+0.2
stress
7H9 with Meropenem 9.6 ug/mL
-0.1
-0.3
-0.3
-0.2
+0.1
stress
7H9 with Ethionamide 0.1 ug/mL
-0.4
-0.2
-0.4
-0.1
+0.3
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.1
-0.2
-0.6
-0.0
+0.1
stress
7H9 with Hygromycin B 0.0095 mM
+0.1
-0.5
-0.3
-0.2
+0.1
stress
7H9 with Meropenem 9.6 ug/mL
-0.2
-0.3
-0.1
-0.3
+0.2
no stress control
no stress control
-0.1
-0.4
-0.2
-0.2
+0.2
stress
7H9 with Delamanid 0.236 ug/mL
-0.2
-0.2
-0.3
-0.1
+0.1
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.1
-0.4
-0.1
-0.1
+0.1
stress
7H9 with Rifampicin 0.014 ug/mL
-0.1
-0.3
-0.2
-0.3
+0.2
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.0
-0.3
-0.5
+0.2
+0.0
stress
7H9 with Rifampicin 0.00045 ug/mL
-0.1
-0.2
-0.2
-0.2
+0.2
no stress control
no stress control
-0.3
+0.4
-0.5
-0.3
+0.3
stress
7H9 with Rifampicin 0.014 ug/mL
-0.2
-0.4
-0.1
+0.1
+0.2
carbon source
D-Trehalose 10 mM (C)
-0.2
-0.4
-0.0
+0.2
+0.1
stress
7H9 with Clarithromycin 0.967 ug/mL
+0.0
-0.4
-0.3
+0.2
+0.2
carbon source
L-Glutamine (C)
-0.1
-0.5
+0.1
+0.1
+0.2
carbon source
L-Glutamine (C)
-0.1
-0.3
-0.1
+0.3
-0.0
nitrogen source
L-Glutamic 10 mM (N)
-0.3
+0.0
-0.3
+0.3
+0.0
carbon source
L-Lactate 10 mM (C)
-0.1
-0.2
-0.2
+0.2
+0.2
carbon source
propionate (C)
-0.1
-0.3
-0.1
+0.1
+0.3
carbon source
Valeric 10 mM (C)
+0.2
-0.3
-0.0
+0.3
-0.1
carbon source
Palmitic 100 uM (C)
+0.3
-0.2
+0.2
+0.1
+0.1
carbon source
pyruvate (C)
+0.1
-0.3
+0.1
+0.2
+0.5
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