Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3156 and Rv3157 overlap by 4 nucleotidesRv3157 and Rv3158 overlap by 4 nucleotidesRv3158 and Rv3159c are separated by 5 nucleotidesRv3159c and Rv3160c are separated by 174 nucleotides Rv3156: Rv3156 - Probable NADH dehydrogenase I (chain L) NuoL (NADH-ubiquinone oxidoreductase chain L), at 3,522,234 to 3,524,135 Rv3156 Rv3157: Rv3157 - Probable NADH dehydrogenase I (chain M) NUOK (NADH-ubiquinone oxidoreductase chain M), at 3,524,132 to 3,525,793 Rv3157 Rv3158: Rv3158 - Probable NADH dehydrogenase I (chain N) NuoN (NADH-ubiquinone oxidoreductase chain N), at 3,525,790 to 3,527,385 Rv3158 Rv3159c: Rv3159c - PPE family protein PPE53, at 3,527,391 to 3,529,163 Rv3159c Rv3160c: Rv3160c - Possible transcriptional regulatory protein (probably TetR-family), at 3,529,338 to 3,529,979 Rv3160c
Group Condition Rv3156 Rv3157 Rv3158 Rv3159c Rv3160c
carbon source propionate (C) -2.7 -2.6 -2.1 +0.1 N.D.
carbon source propionate (C) -2.6 -2.2 -2.2 +0.1 N.D.
carbon source L-Asparagine (C) -1.4 -1.6 -1.4 +0.4 N.D.
carbon source L-Asparagine (C) -1.1 -1.1 -1.3 +0.1 N.D.
carbon source Valeric 10 mM (C) -0.8 -1.1 -1.3 -0.0 N.D.
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.9 -0.9 -1.0 -0.2 N.D.
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM -0.9 -1.4 -0.7 +0.2 N.D.
carbon source cholesterol 100uM (C) -0.6 -0.8 -0.8 -0.0 N.D.
stress 7H9 with Chlorpromazine 0.054 mM -0.5 -0.8 -0.6 -0.2 N.D.
carbon source Glycerol (C) -0.6 -0.8 -0.6 -0.0 N.D.
carbon source pyruvate (C) -0.7 -0.6 -0.6 -0.0 N.D.
stress 7H9 with Chlorpromazine 0.054 mM -0.7 -0.9 -0.3 +0.1 N.D.
carbon source cholesterol 100uM (C) -0.6 -0.8 -0.6 +0.2 N.D.
carbon source pyruvate (C) -0.9 -0.5 -0.5 +0.2 N.D.
nitrogen source Ammonium chloride 10mM (N) -1.1 -0.3 -0.3 +0.2 N.D.
carbon source Glycerol (C) -0.6 -0.6 -0.5 +0.2 N.D.
carbon source Palmitic 100 uM (C) -0.7 -0.4 -0.6 +0.3 N.D.
no stress control no stress control -0.5 -0.1 -0.9 +0.2 N.D.
carbon source Valeric 10 mM (C) -0.5 -0.6 -0.3 +0.2 N.D.
no stress control no stress control -0.6 -0.5 -0.4 +0.3 N.D.
nitrogen source Ammonium chloride 10mM (N) -0.5 -0.4 -0.4 +0.1 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL -0.2 +0.8 +0.0 +0.3 N.D.
nitrogen source L-Alanine 10 mM (N) +0.4 +0.3 +0.5 +0.3 N.D.
nitrogen source L-Asparagine 10 mM (N) +0.3 +0.5 +0.6 +0.2 N.D.
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.4 +0.6 +0.3 +0.3 N.D.
nitrogen source L-Alanine 10 mM (N) +0.6 +0.3 +0.8 -0.0 N.D.
nitrogen source L-Serine 10 mM (N) +0.5 +0.5 +0.6 +0.1 N.D.
pH pH 4.5 +0.5 +1.1 +0.4 -0.2 N.D.
pH pH 4.5 +0.4 +0.8 +0.9 -0.2 N.D.
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.6 +0.5 +0.8 +0.2 N.D.
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