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Protein
Homologs
Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv3068c and Rv3069 are separated by 69 nucleotides
Rv3069 and Rv3070 overlap by 4 nucleotides
Rv3070 and Rv3071 overlap by 4 nucleotides
Rv3071 and Rv3072c are separated by 224 nucleotides
Rv3068c: Rv3068c - Probable phosphoglucomutase PgmA (glucose phosphomutase) (PGM), at 3,431,979 to 3,433,622
Rv3068c
Rv3069: Rv3069 - Probable conserved transmembrane protein, at 3,433,692 to 3,434,090
Rv3069
Rv3070: Rv3070 - Probable conserved integral membrane protein, at 3,434,087 to 3,434,467
Rv3070
Rv3071: Rv3071 - Conserved hypothetical protein, at 3,434,464 to 3,435,573
Rv3071
Rv3072c: Rv3072c - Conserved hypothetical protein, at 3,435,798 to 3,436,322
Rv3072c
Group
Condition
Rv3068c
Rv3069
Rv3070
Rv3071
Rv3072c
no stress control
no stress control
-0.2
-0.9
-0.2
+0.0
-0.7
stress
7H9 with Clarithromycin 0.967 ug/mL
-0.2
-0.3
-0.4
-0.5
-0.5
pH
pH 5.5
-0.1
-1.0
-0.2
-0.5
+0.0
carbon source
D-Trehalose 10 mM (C)
-0.6
-0.4
-0.4
+0.1
-0.2
stress
7H9 with Linezolid 0.3 ug/mL
+0.0
-0.7
-0.4
-0.0
-0.2
carbon source
cholesterol 100uM (C)
+0.0
-0.7
-0.2
-0.1
-0.3
stress
7H9 with Plumbagin 0.01 mM
-0.1
-0.9
+0.0
-0.3
+0.0
stress
7H9 with Tetrazolium violet 0.065 mM
-0.1
-0.5
-0.5
+0.1
-0.2
stress
7H9 with Ramoplanin 0.009 mM
+0.0
-0.6
+0.1
+0.1
-0.6
no stress control
no stress control
-0.1
-0.2
-0.4
+0.3
-0.5
carbon source
D-Trehalose 10 mM (C)
-0.7
-0.3
-0.1
+0.2
-0.0
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
-0.1
-0.2
-0.3
+0.2
-0.5
stress
7H9 with Linezolid 0.3 ug/mL
-0.1
-0.3
-0.5
-0.2
+0.2
no stress control
no stress control
-0.2
-0.4
-0.4
+0.2
+0.2
stress
7H9 with Erythromycin 0.016 mM
-0.0
+0.3
-0.6
+0.0
-0.4
carbon source
propionate (C)
+0.1
-0.9
-0.0
+0.2
+0.3
stress
7H9 with Dibucaine 0.21 mM
-0.2
+0.3
-0.3
-0.3
+0.2
stress
7H9 with Isoniazid 0.025 ug/mL
+0.1
+0.8
-0.7
-0.1
-0.2
stress
7H9 with Chlorpromazine 0.054 mM
+0.3
-0.4
-0.2
-0.1
+0.4
stress
7H9 with Lomefloxacin 0.0035 mM
+0.3
+0.3
+0.1
+0.1
-0.5
stress
7H9 with Nickel (II) chloride 0.6 mM
+0.4
+0.5
-0.4
+0.0
-0.2
stress
7H9 with methylglyoxal 1.2 mM
-0.2
+0.4
+0.1
+0.5
-0.4
stress
7H9 with Ethionamide 0.1 ug/mL
+0.1
+0.5
-0.3
-0.1
+0.4
stress
7H9 with nitrite 1.5 mM; pH 5.5
-0.0
+0.1
+0.4
-0.5
+0.6
stress
7H9 with Novobiocin 0.004 mM
-0.2
-0.1
+0.7
+0.4
+0.1
stress
7H9 with Levofloxacin 0.3 ug/mL
+0.1
+0.9
+0.0
+0.2
-0.2
carbon source
L-Aspartic Acid (C)
+0.2
+0.1
+0.1
+0.4
+0.4
stress
7H9 with Meropenem 9.6 ug/mL
+0.0
+0.8
+0.4
+0.3
-0.1
stress
7H9 with Doxycycline hyclate 0.0035 mM
+0.1
+0.5
-0.1
+0.2
+0.7
no stress control
no stress control
-0.0
+0.8
+0.4
+0.3
+0.1
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