Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv3068c and Rv3069 are separated by 69 nucleotidesRv3069 and Rv3070 overlap by 4 nucleotidesRv3070 and Rv3071 overlap by 4 nucleotidesRv3071 and Rv3072c are separated by 224 nucleotides Rv3068c: Rv3068c - Probable phosphoglucomutase PgmA (glucose phosphomutase) (PGM), at 3,431,979 to 3,433,622 Rv3068c Rv3069: Rv3069 - Probable conserved transmembrane protein, at 3,433,692 to 3,434,090 Rv3069 Rv3070: Rv3070 - Probable conserved integral membrane protein, at 3,434,087 to 3,434,467 Rv3070 Rv3071: Rv3071 - Conserved hypothetical protein, at 3,434,464 to 3,435,573 Rv3071 Rv3072c: Rv3072c - Conserved hypothetical protein, at 3,435,798 to 3,436,322 Rv3072c
Group Condition Rv3068c Rv3069 Rv3070 Rv3071 Rv3072c
no stress control no stress control -0.2 -0.9 -0.2 +0.0 -0.7
stress 7H9 with Clarithromycin 0.967 ug/mL -0.2 -0.3 -0.4 -0.5 -0.5
pH pH 5.5 -0.1 -1.0 -0.2 -0.5 +0.0
carbon source D-Trehalose 10 mM (C) -0.6 -0.4 -0.4 +0.1 -0.2
stress 7H9 with Linezolid 0.3 ug/mL +0.0 -0.7 -0.4 -0.0 -0.2
carbon source cholesterol 100uM (C) +0.0 -0.7 -0.2 -0.1 -0.3
stress 7H9 with Plumbagin 0.01 mM -0.1 -0.9 +0.0 -0.3 +0.0
stress 7H9 with Tetrazolium violet 0.065 mM -0.1 -0.5 -0.5 +0.1 -0.2
stress 7H9 with Ramoplanin 0.009 mM +0.0 -0.6 +0.1 +0.1 -0.6
no stress control no stress control -0.1 -0.2 -0.4 +0.3 -0.5
carbon source D-Trehalose 10 mM (C) -0.7 -0.3 -0.1 +0.2 -0.0
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.1 -0.2 -0.3 +0.2 -0.5
stress 7H9 with Linezolid 0.3 ug/mL -0.1 -0.3 -0.5 -0.2 +0.2
no stress control no stress control -0.2 -0.4 -0.4 +0.2 +0.2
stress 7H9 with Erythromycin 0.016 mM -0.0 +0.3 -0.6 +0.0 -0.4
carbon source propionate (C) +0.1 -0.9 -0.0 +0.2 +0.3
stress 7H9 with Dibucaine 0.21 mM -0.2 +0.3 -0.3 -0.3 +0.2
stress 7H9 with Isoniazid 0.025 ug/mL +0.1 +0.8 -0.7 -0.1 -0.2
stress 7H9 with Chlorpromazine 0.054 mM +0.3 -0.4 -0.2 -0.1 +0.4
stress 7H9 with Lomefloxacin 0.0035 mM +0.3 +0.3 +0.1 +0.1 -0.5
stress 7H9 with Nickel (II) chloride 0.6 mM +0.4 +0.5 -0.4 +0.0 -0.2
stress 7H9 with methylglyoxal 1.2 mM -0.2 +0.4 +0.1 +0.5 -0.4
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 +0.5 -0.3 -0.1 +0.4
stress 7H9 with nitrite 1.5 mM; pH 5.5 -0.0 +0.1 +0.4 -0.5 +0.6
stress 7H9 with Novobiocin 0.004 mM -0.2 -0.1 +0.7 +0.4 +0.1
stress 7H9 with Levofloxacin 0.3 ug/mL +0.1 +0.9 +0.0 +0.2 -0.2
carbon source L-Aspartic Acid (C) +0.2 +0.1 +0.1 +0.4 +0.4
stress 7H9 with Meropenem 9.6 ug/mL +0.0 +0.8 +0.4 +0.3 -0.1
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.1 +0.5 -0.1 +0.2 +0.7
no stress control no stress control -0.0 +0.8 +0.4 +0.3 +0.1
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