Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2973c and Rv2974c are separated by 2 nucleotidesRv2974c and Rv2975c overlap by 4 nucleotidesRv2975c and Rv2976c are separated by 458 nucleotidesRv2976c and Rv2977c are separated by 32 nucleotides Rv2973c: Rv2973c - Probable ATP-dependent DNA helicase RecG, at 3,327,733 to 3,329,946 Rv2973c Rv2974c: Rv2974c - Conserved hypothetical alanine rich protein, at 3,329,949 to 3,331,361 Rv2974c Rv2975c: Rv2975c - Conserved hypothetical protein, at 3,331,358 to 3,331,612 Rv2975c Rv2976c: Rv2976c - Probable uracil-DNA glycosylase Ung (UDG), at 3,332,071 to 3,332,754 Rv2976c Rv2977c: Rv2977c - Probable thiamine-monophosphate kinase ThiL (thiamine-phosphate kinase), at 3,332,787 to 3,333,788 Rv2977c
Group Condition Rv2973c Rv2974c Rv2975c Rv2976c Rv2977c
carbon source butyrate 10 mM (C) -0.6 -0.1 -1.3 -0.3 N.D.
carbon source Palmitic 100 uM (C) -0.5 -0.2 -1.6 +0.0 N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.4 -0.4 -1.0 -0.1 N.D.
carbon source Glycerol (C) -0.6 -0.1 -0.7 -0.3 N.D.
stress 7H9 with Clarithromycin 0.967 ug/mL -0.4 +0.1 +0.2 -1.1 N.D.
carbon source L-Aspartic Acid (C) -0.3 -0.2 +0.3 -0.9 N.D.
carbon source D-Glucose (C) -0.6 +0.0 -0.6 +0.4 N.D.
stress 7H9 with Rifampicin 0.00045 ug/mL -0.3 -0.0 -1.0 +0.6 N.D.
carbon source Stearic 100 uM (C) -0.1 -0.1 -0.9 +0.5 N.D.
stress 7H9 with Rifampicin 0.014 ug/mL -0.4 -0.0 -0.5 +0.8 N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL -0.8 -0.1 +0.1 +0.6 N.D.
nitrogen source L-Asparagine 10 mM (N) -0.2 -0.1 -0.7 +0.9 N.D.
nitrogen source L-Serine 10 mM (N) -0.1 -0.1 -0.8 +0.9 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL -0.2 -0.1 +1.0 -0.4 N.D.
carbon source D-Trehalose 10 mM (C) +0.1 -0.0 -0.9 +1.4 N.D.
stress 7H9 with Rifampicin 0.014 ug/mL -0.2 -0.3 +0.5 +0.9 N.D.
nitrogen source L-Glutamine 10 mM (N) -0.0 -0.1 -0.4 +1.4 N.D.
carbon source casaminos 1 mg/mL (C) -0.5 +0.1 +1.0 +0.2 N.D.
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.1 -0.2 +1.1 +0.2 N.D.
stress 7H9 with Pretomanid 0.213 ug/mL -0.2 -0.2 +0.3 +1.3 N.D.
stress 7H9 with Linezolid 0.44 ug/mL -0.3 -0.1 +0.8 +0.9 N.D.
nitrogen source L-Glutamine 10 mM (N) -0.2 -0.1 +0.8 +0.8 N.D.
nitrogen source L-Asparagine 10 mM (N) -0.3 -0.1 +0.2 +1.6 N.D.
carbon source L-Lactate 10 mM (C) -0.1 +0.1 +0.7 +0.9 N.D.
nitrogen source L-Glutamic 10 mM (N) +0.2 -0.2 +0.6 +1.0 N.D.
carbon source D-Trehalose 10 mM (C) -0.1 +0.0 +1.1 +0.6 N.D.
nitrogen source L-Valine 10 mM (N) +0.4 +0.2 +0.3 +0.8 N.D.
carbon source D-Lactate 10 mM (C) -0.0 +0.0 +1.1 +1.0 N.D.
nitrogen source L-Glutamic 10 mM (N) -0.0 -0.1 +1.4 +1.2 N.D.
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 -0.1 +0.1 +2.3 N.D.
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