Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2967c and Rv2968c are separated by 24 nucleotidesRv2968c and Rv2969c are separated by 5 nucleotidesRv2969c and Rv2970c are separated by 96 nucleotidesRv2970c and Rv2970A are separated by 230 nucleotides Rv2967c: Rv2967c - Probable pyruvate carboxylase Pca (pyruvic carboxylase), at 3,319,663 to 3,323,046 Rv2967c Rv2968c: Rv2968c - Probable conserved integral membrane protein, at 3,323,071 to 3,323,703 Rv2968c Rv2969c: Rv2969c - Possible conserved membrane or secreted protein, at 3,323,709 to 3,324,476 Rv2969c Rv2970c: Rv2970c - Probable lipase/esterase LipN, at 3,324,573 to 3,325,703 Rv2970c Rv2970A: Rv2970A - Conserved hypothetical protein, at 3,325,934 to 3,326,104 Rv2970A
Group Condition Rv2967c Rv2968c Rv2969c Rv2970c Rv2970A
nitrogen source Ammonium chloride 10mM (N) -4.4 N.D. N.D. -0.2 -0.2
nitrogen source Glycine 10 mM (N) -3.8 N.D. N.D. -0.3 -0.5
nitrogen source L-Serine 10 mM (N) -4.1 N.D. N.D. -0.2 -0.2
nitrogen source L-Serine 10 mM (N) -4.2 N.D. N.D. -0.1 -0.1
nitrogen source Glycine 10 mM (N) -4.0 N.D. N.D. -0.2 -0.1
nitrogen source L-Alanine 10 mM (N) -3.5 N.D. N.D. -0.3 -0.5
nitrogen source L-Alanine 10 mM (N) -3.5 N.D. N.D. -0.3 -0.2
nitrogen source Ammonium chloride 10mM (N) -3.5 N.D. N.D. -0.1 -0.4
nitrogen source Urea 10mM (N) -3.0 N.D. N.D. -0.4 -0.0
nitrogen source Urea 10mM (N) -2.6 N.D. N.D. -0.1 -0.2
nitrogen source L-Valine 10 mM (N) -2.0 N.D. N.D. -0.3 -0.3
nitrogen source L-Valine 10 mM (N) -2.3 N.D. N.D. -0.0 +0.1
stress 7H9 with Benzethonium chloride 0.068 mM -0.7 N.D. N.D. -0.5 -0.6
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.0 N.D. N.D. -0.1 -0.4
stress 7H9 with Menadione 0.005 mM -1.0 N.D. N.D. +0.1 -0.3
stress 7H9 with Benzethonium chloride 0.068 mM -0.7 N.D. N.D. -0.1 -0.4
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.8 N.D. N.D. -0.1 -0.3
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 -0.7 N.D. N.D. +0.1 -0.4
stress 7H9 with Chlorhexidine diacetate salt 0.0021 mM -0.7 N.D. N.D. -0.2 +0.1
stress 7H9 with Menadione 0.005 mM -0.9 N.D. N.D. +0.0 +0.2
no stress control no stress control +0.2 N.D. N.D. -0.4 -0.5
stress 7H9 with Phenazine ethosulfate 0.0137 mM +0.5 N.D. N.D. -0.2 -0.6
carbon source oleate 200uM (C) +0.5 N.D. N.D. -0.3 -0.4
stress 7H9 with Hydrogen peroxide 3.97 mM -0.7 N.D. N.D. +0.3 +0.4
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.8 N.D. N.D. -0.3 -0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.8 N.D. N.D. -0.1 +0.2
stress 7H9 with Sisomicin 0.07 mM +0.8 N.D. N.D. +0.0 +0.3
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.8 N.D. N.D. +0.0 +0.4
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +1.3 N.D. N.D. -0.1 +0.1
stress 7H9 with Sisomicin 0.07 mM +1.0 N.D. N.D. +0.1 +1.0
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