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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2928 and Rv2929 overlap by 14 nucleotides
Rv2929 and Rv2930 are separated by 415 nucleotides
Rv2930 and Rv2931 overlap by 4 nucleotides
Rv2931 and Rv2932 overlap by 4 nucleotides
Rv2928: Rv2928 - Probable thioesterase TesA, at 3,242,198 to 3,242,983
Rv2928
Rv2929: Rv2929 - Hypothetical protein, at 3,242,970 to 3,243,281
Rv2929
Rv2930: Rv2930 - Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase), at 3,243,697 to 3,245,448
Rv2930
Rv2931: Rv2931 - Phenolpthiocerol synthesis type-I polyketide synthase PpsA, at 3,245,445 to 3,251,075
Rv2931
Rv2932: Rv2932 - Phenolpthiocerol synthesis type-I polyketide synthase PpsB, at 3,251,072 to 3,255,688
Rv2932
Group
Condition
Rv2928
Rv2929
Rv2930
Rv2931
Rv2932
nitrogen source
L-Aspartic Acid 10 mM (N)
+1.2
+1.5
+1.4
+1.2
+1.3
stress
7H9 with Zinc Pyrithione 0.00072 mM
+1.2
+1.8
+1.2
+1.3
+1.3
nitrogen source
Glycine 10 mM (N)
+1.3
+1.5
+1.4
+1.3
+1.3
carbon source
L-Lactate 10 mM (C)
+1.3
+1.2
+1.5
+1.5
+1.5
carbon source
L-Glutamine (C)
+0.8
+1.4
+1.7
+1.7
+1.6
stress
7H9 with Dicloxacillin 0.0069 mM
+1.2
+1.4
+1.6
+1.5
+1.5
no stress control
no stress control
+1.5
+1.3
+1.5
+1.5
+1.5
pH
pH 4.5
+1.6
+1.2
+1.5
+1.6
+1.6
carbon source
L-Glutamine (C)
+0.8
+1.5
+1.7
+1.7
+1.7
stress
7H9 with Amikacin di2 ug/mL
+1.4
+1.2
+1.6
+1.7
+1.7
carbon source
L-Lactate 10 mM (C)
+1.4
+1.7
+1.6
+1.5
+1.6
nitrogen source
Glycine 10 mM (N)
+1.5
+1.5
+1.7
+1.7
+1.7
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
+1.7
+1.7
+1.7
+1.7
+1.6
stress
7H9 with Dimethyl Sulfoxide 1 vol%
+1.6
+1.3
+1.8
+1.9
+1.8
no stress control
no stress control
+1.4
+1.8
+1.7
+1.8
+1.9
stress
7H9 with Dicloxacillin 0.0069 mM
+1.9
+1.7
+1.7
+1.8
+1.9
stress
7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
+2.0
+1.6
+1.9
+1.8
+1.8
stress
7H9 with Dimethyl Sulfoxide 1 vol%
+1.8
+1.6
+2.0
+2.0
+2.0
no stress control
no stress control
+2.1
+1.9
+1.8
+1.9
+1.8
no stress control
no stress control
+2.3
+2.0
+1.9
+1.9
+1.8
stress
7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
+2.0
+2.1
+2.0
+2.0
+2.0
nitrogen source
L-Asparagine 10 mM (N)
+1.8
+2.2
+2.1
+2.1
+2.1
stress
7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
+2.3
+1.9
+2.1
+2.1
+2.2
carbon source
oleate 200uM (C)
+2.3
+1.2
+2.2
+2.6
+2.6
nitrogen source
L-Asparagine 10 mM (N)
+2.1
+2.5
+2.5
+2.4
+2.6
carbon source
oleate 200uM (C)
+2.5
+1.5
+2.4
+3.0
+3.0
nitrogen source
L-Glutamine 10 mM (N)
+3.2
+3.3
+3.8
+3.7
+3.7
nitrogen source
L-Glutamine 10 mM (N)
+3.1
+3.6
+3.9
+3.8
+4.0
nitrogen source
L-Glutamic 10 mM (N)
+3.3
+2.8
+4.7
+4.7
+4.7
nitrogen source
L-Glutamic 10 mM (N)
+3.6
+3.0
+4.8
+4.8
+4.8
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