Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2928 and Rv2929 overlap by 14 nucleotidesRv2929 and Rv2930 are separated by 415 nucleotidesRv2930 and Rv2931 overlap by 4 nucleotidesRv2931 and Rv2932 overlap by 4 nucleotides Rv2928: Rv2928 - Probable thioesterase TesA, at 3,242,198 to 3,242,983 Rv2928 Rv2929: Rv2929 - Hypothetical protein, at 3,242,970 to 3,243,281 Rv2929 Rv2930: Rv2930 - Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase), at 3,243,697 to 3,245,448 Rv2930 Rv2931: Rv2931 - Phenolpthiocerol synthesis type-I polyketide synthase PpsA, at 3,245,445 to 3,251,075 Rv2931 Rv2932: Rv2932 - Phenolpthiocerol synthesis type-I polyketide synthase PpsB, at 3,251,072 to 3,255,688 Rv2932
Group Condition Rv2928 Rv2929 Rv2930 Rv2931 Rv2932
nitrogen source L-Aspartic Acid 10 mM (N) +1.2 +1.5 +1.4 +1.2 +1.3
stress 7H9 with Zinc Pyrithione 0.00072 mM +1.2 +1.8 +1.2 +1.3 +1.3
nitrogen source Glycine 10 mM (N) +1.3 +1.5 +1.4 +1.3 +1.3
carbon source L-Lactate 10 mM (C) +1.3 +1.2 +1.5 +1.5 +1.5
carbon source L-Glutamine (C) +0.8 +1.4 +1.7 +1.7 +1.6
stress 7H9 with Dicloxacillin 0.0069 mM +1.2 +1.4 +1.6 +1.5 +1.5
no stress control no stress control +1.5 +1.3 +1.5 +1.5 +1.5
pH pH 4.5 +1.6 +1.2 +1.5 +1.6 +1.6
carbon source L-Glutamine (C) +0.8 +1.5 +1.7 +1.7 +1.7
stress 7H9 with Amikacin di2 ug/mL +1.4 +1.2 +1.6 +1.7 +1.7
carbon source L-Lactate 10 mM (C) +1.4 +1.7 +1.6 +1.5 +1.6
nitrogen source Glycine 10 mM (N) +1.5 +1.5 +1.7 +1.7 +1.7
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +1.7 +1.7 +1.7 +1.7 +1.6
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.6 +1.3 +1.8 +1.9 +1.8
no stress control no stress control +1.4 +1.8 +1.7 +1.8 +1.9
stress 7H9 with Dicloxacillin 0.0069 mM +1.9 +1.7 +1.7 +1.8 +1.9
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +2.0 +1.6 +1.9 +1.8 +1.8
stress 7H9 with Dimethyl Sulfoxide 1 vol% +1.8 +1.6 +2.0 +2.0 +2.0
no stress control no stress control +2.1 +1.9 +1.8 +1.9 +1.8
no stress control no stress control +2.3 +2.0 +1.9 +1.9 +1.8
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +2.0 +2.1 +2.0 +2.0 +2.0
nitrogen source L-Asparagine 10 mM (N) +1.8 +2.2 +2.1 +2.1 +2.1
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +2.3 +1.9 +2.1 +2.1 +2.2
carbon source oleate 200uM (C) +2.3 +1.2 +2.2 +2.6 +2.6
nitrogen source L-Asparagine 10 mM (N) +2.1 +2.5 +2.5 +2.4 +2.6
carbon source oleate 200uM (C) +2.5 +1.5 +2.4 +3.0 +3.0
nitrogen source L-Glutamine 10 mM (N) +3.2 +3.3 +3.8 +3.7 +3.7
nitrogen source L-Glutamine 10 mM (N) +3.1 +3.6 +3.9 +3.8 +4.0
nitrogen source L-Glutamic 10 mM (N) +3.3 +2.8 +4.7 +4.7 +4.7
nitrogen source L-Glutamic 10 mM (N) +3.6 +3.0 +4.8 +4.8 +4.8
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