Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2901c and Rv2902c are separated by 53 nucleotidesRv2902c and Rv2903c are separated by 13 nucleotidesRv2903c and Rv2904c are separated by 57 nucleotidesRv2904c and Rv2905 are separated by 374 nucleotides Rv2901c: Rv2901c - Conserved protein, at 3,211,803 to 3,212,108 Rv2901c Rv2902c: Rv2902c - Probable ribonuclease HII protein RnhB (RNase HII), at 3,212,162 to 3,212,956 Rv2902c Rv2903c: Rv2903c - Probable signal peptidase I LepB (SPASE I) (leader peptidase I)., at 3,212,970 to 3,213,854 Rv2903c Rv2904c: Rv2904c - 50S ribosomal protein L19 RplS, at 3,213,912 to 3,214,253 Rv2904c Rv2905: Rv2905 - Probable conserved alanine rich lipoprotein LppW, at 3,214,628 to 3,215,572 Rv2905
Group Condition Rv2901c Rv2902c Rv2903c Rv2904c Rv2905
carbon source D-Trehalose 10 mM (C) -0.7 -0.0 N.D. N.D. -0.5
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.7 -1.4 N.D. N.D. +0.0
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 -0.5 N.D. N.D. +0.2
stress 7H9 with Isoniazid 0.025 ug/mL +0.3 -0.5 N.D. N.D. +0.2
carbon source Palmitic 100 uM (C) +0.8 -0.4 N.D. N.D. -0.0
nitrogen source L-Glutamine 10 mM (N) +0.3 +0.4 N.D. N.D. -0.3
carbon source heptadecanoic 250 uM (C) +0.7 -0.0 N.D. N.D. -0.3
stress 7H9 with Clofazimine 0.45 ug/mL +0.6 -0.3 N.D. N.D. +0.2
stress 7H9 with Pretomanid 0.213 ug/mL +0.9 -0.1 N.D. N.D. -0.2
carbon source Stearic 100 uM (C) +0.5 +0.4 N.D. N.D. -0.1
nitrogen source L-Glutamic 10 mM (N) +0.7 +0.3 N.D. N.D. -0.1
nitrogen source L-Glutamic 10 mM (N) +0.7 +0.2 N.D. N.D. -0.0
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.9 -0.3 N.D. N.D. +0.3
stress 7H9 with Clarithromycin 0.967 ug/mL +0.2 +0.4 N.D. N.D. +0.3
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.9 -0.1 N.D. N.D. +0.1
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.7 +0.4 N.D. N.D. -0.1
carbon source butyrate 10 mM (C) +0.4 +0.5 N.D. N.D. +0.1
stress 7H9 with Rifampicin 0.00045 ug/mL +0.7 -0.0 N.D. N.D. +0.3
no stress control no stress control +0.7 +0.3 N.D. N.D. +0.0
carbon source heptadecanoic 250 uM (C) +0.9 +0.3 N.D. N.D. -0.2
nitrogen source L-Aspartic Acid 10 mM (N) +0.8 +0.2 N.D. N.D. +0.0
carbon source Palmitic 100 uM (C) +0.7 +0.3 N.D. N.D. -0.1
stress 7H9 with Hygromycin B 0.0095 mM +0.8 +0.2 N.D. N.D. +0.0
stress 7H9 with Streptomycin 0.178 ug/mL +0.8 -0.0 N.D. N.D. +0.2
stress 7H9 with Clarithromycin 0.967 ug/mL +0.5 +0.5 N.D. N.D. +0.2
nitrogen source L-Asparagine 10 mM (N) +0.6 +0.4 N.D. N.D. +0.3
no stress control no stress control +0.7 +0.3 N.D. N.D. +0.2
stress 7H9 with Rifampicin 0.014 ug/mL +0.8 +0.1 N.D. N.D. +0.6
stress 7H9 with Rifampicin 0.014 ug/mL +0.9 -0.1 N.D. N.D. +0.8
stress 7H9 with Streptomycin 0.178 ug/mL +1.0 +0.6 N.D. N.D. +0.1
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