Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2897c and Rv2898c overlap by 1 nucleotidesRv2898c and Rv2899c are separated by 247 nucleotidesRv2899c and Rv2900c overlap by 1 nucleotidesRv2900c and Rv2901c are separated by 57 nucleotides Rv2897c: Rv2897c - Conserved hypothetical protein, at 3,206,431 to 3,207,942 Rv2897c Rv2898c: Rv2898c - Conserved hypothetical protein, at 3,207,942 to 3,208,328 Rv2898c Rv2899c: Rv2899c - Possible FdhD protein homolog, at 3,208,576 to 3,209,406 Rv2899c Rv2900c: Rv2900c - Possible formate dehydrogenase H FdhF (formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide) (formate dehydrogenase-H alpha subunit) (FDH-H), at 3,209,406 to 3,211,745 Rv2900c Rv2901c: Rv2901c - Conserved protein, at 3,211,803 to 3,212,108 Rv2901c
Group Condition Rv2897c Rv2898c Rv2899c Rv2900c Rv2901c
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 -2.1 +0.6 -0.1 -0.1
nitrogen source L-Valine 10 mM (N) -0.3 -0.5 -1.0 -0.2 +0.3
stress 7H9 with Levofloxacin 0.3 ug/mL +0.4 -2.2 -0.2 -0.1 +0.5
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.6 -2.7 +0.1 -0.1 +0.9
carbon source L-Lactate 10 mM (C) -0.1 -1.6 +0.6 +0.2 -0.3
stress 7H9 with Ofloxacin 0.8 ug/mL +0.1 -2.3 +0.9 +0.2 +0.4
carbon source heptadecanoic 250 uM (C) -0.1 -1.0 -0.6 +0.2 +0.9
carbon source L-Aspartic Acid (C) +0.4 -1.6 +0.7 +0.0 -0.1
stress 7H9 with Sulfamethizole 0.026 mM +0.1 -1.3 +0.2 +0.0 +0.5
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.2 -0.8 +0.3 -0.3 +0.7
no stress control no stress control -0.2 -1.5 +1.7 -0.2 +0.4
stress 7H9 with Isoniazid 0.025 ug/mL +0.9 -1.8 +0.9 +0.1 +0.3
carbon source Palmitic 100 uM (C) -0.3 -0.4 +0.5 -0.0 +0.8
carbon source Stearic 100 uM (C) -0.3 -0.5 +0.6 +0.2 +0.5
stress 7H9 with Pretomanid 0.213 ug/mL +0.5 -1.3 +0.9 +0.0 +0.6
stress 7H9 with Linezolid 0.44 ug/mL +0.1 +1.3 -0.8 +0.1 +0.2
stress 7H9 with Rifampicin 0.014 ug/mL -0.2 +0.8 -0.6 +0.1 +0.9
stress 7H9 with Pretomanid 0.213 ug/mL -0.3 +0.6 -0.2 +0.1 +0.9
no stress control no stress control +0.0 -0.5 +0.8 +0.0 +0.7
stress 7H9 with Meropenem 9.6 ug/mL +1.0 -0.6 +0.3 -0.0 +0.6
stress 7H9 with Clarithromycin 0.967 ug/mL -0.3 +1.0 -0.1 +0.3 +0.5
stress 7H9 with Rifampicin 0.00045 ug/mL -0.0 +1.2 -0.5 +0.1 +0.7
nitrogen source L-Glutamine 10 mM (N) -0.6 -0.1 +1.9 +0.1 +0.3
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 -0.2 +1.1 -0.0 +0.8
no stress control no stress control +0.7 -0.1 +0.8 +0.1 +0.7
nitrogen source L-Glutamine 10 mM (N) -0.3 +0.2 +1.8 +0.0 +0.5
stress 7H9 with Rifampicin 0.014 ug/mL -0.1 +0.9 +0.4 +0.1 +0.8
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.3 +0.2 +1.0 +0.2 +0.9
nitrogen source L-Glutamic 10 mM (N) +0.2 +0.1 +2.2 -0.1 +0.7
nitrogen source L-Glutamic 10 mM (N) -0.1 +0.8 +2.4 -0.3 +0.7
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