Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2883c and Rv2884 are separated by 234 nucleotidesRv2884 and Rv2885c are separated by 14 nucleotidesRv2885c and Rv2886c overlap by 4 nucleotidesRv2886c and Rv2887 overlap by 2 nucleotides Rv2883c: Rv2883c - Probable uridylate kinase PyrH (UK) (uridine monophosphate kinase) (UMP kinase), at 3,192,373 to 3,193,158 Rv2883c Rv2884: Rv2884 - Probable transcriptional regulatory protein, at 3,193,393 to 3,194,151 Rv2884 Rv2885c: Rv2885c - Probable transposase, at 3,194,166 to 3,195,548 Rv2885c Rv2886c: Rv2886c - Probable resolvase, at 3,195,545 to 3,196,432 Rv2886c Rv2887: Rv2887 - Probable transcriptional regulatory protein, at 3,196,431 to 3,196,850 Rv2887
Group Condition Rv2883c Rv2884 Rv2885c Rv2886c Rv2887
stress 7H9 with Menadione 0.005 mM N.D. -0.1 +0.0 -0.1 -3.1
stress 7H9 with para-aminosalicylic 0.086 ug/mL N.D. -0.1 -0.1 -0.2 -1.7
stress 7H9 with Formaldehyde 0.23 mM N.D. +0.1 +0.2 +0.1 -2.4
no stress control no stress control N.D. +0.0 +0.1 -0.2 -1.9
stress 7H9 with Cetrimonium bromide 0.015 vol% N.D. -0.0 -0.2 -0.6 -1.0
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. -0.4 -0.3 -0.6 -0.4
no stress control no stress control N.D. -0.1 -0.1 -0.3 -1.3
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. -0.0 -0.2 -0.4 -1.1
stress 7H9 with Dodecyl Sulfate 0.02 vol% N.D. -0.3 -0.1 -0.2 -1.1
stress 7H9 with Dodecyl Sulfate 0.02 vol% N.D. -0.1 -0.1 -0.3 -1.2
stress 7H9 with Dibucaine 0.21 mM N.D. -0.2 -0.2 -0.0 -1.2
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. +0.1 +0.1 -0.0 -1.8
pH pH 4.5 N.D. -0.5 -0.0 -0.2 -0.9
carbon source D-Trehalose 10 mM (C) N.D. -0.3 -0.0 +0.1 -1.2
nitrogen source L-Glutamic 10 mM (N) N.D. -0.1 +0.1 -0.2 -1.2
stress 7H9 with nitrite 3 mM; pH 5.5 N.D. +0.2 -0.0 -0.3 -1.2
stress 7H9 with Plumbagin 0.01 mM N.D. +0.2 +0.1 -0.4 -1.2
no stress control no stress control N.D. +0.4 -0.1 +0.1 -1.4
carbon source Palmitic 100 uM (C) N.D. -0.5 -0.3 -0.4 +0.4
stress 7H9 with Spectinomycin 0.029 mM N.D. -0.0 +0.2 +0.3 -1.1
stress 7H9 with Phenazine ethosulfate 0.0137 mM N.D. -0.7 -0.1 +0.0 +0.9
no stress control no stress control N.D. -0.2 -0.1 -0.3 +0.9
stress 7H9 with Levofloxacin 0.3 ug/mL N.D. -0.3 -0.2 +0.1 +1.0
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. -0.4 +0.2 -0.1 +0.8
stress 7H9 with Ethionamide 0.1 ug/mL N.D. -0.3 -0.0 +0.1 +1.2
stress 7H9 with Novobiocin 0.004 mM N.D. -0.3 -0.1 +0.2 +1.1
stress 7H9 with Amikacin di2 ug/mL N.D. -0.0 +0.1 +0.2 +1.1
carbon source Stearic 100 uM (C) N.D. +0.3 -0.1 -0.1 +1.3
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -0.1 +0.3 -0.1 +1.3
stress 7H9 with Ethionamide 0.1 ug/mL N.D. -0.1 +0.1 +0.1 +1.5
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