Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 236 experiments or choose conditions or try the comparative fitness browser

500 ntRv2846c and Rv2847c are separated by 22 nucleotidesRv2847c and Rv2848c are separated by 276 nucleotidesRv2848c and Rv2849c overlap by 1 nucleotidesRv2849c and Rv2850c are separated by 20 nucleotides Rv2846c: Rv2846c - Possible integral membrane efflux protein EfpA, at 3,153,039 to 3,154,631 Rv2846c Rv2847c: Rv2847c - Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase, at 3,154,654 to 3,155,871 Rv2847c Rv2848c: Rv2848c - Probable cobyrinic acid A,C-diamide synthase CobB, at 3,156,148 to 3,157,521 Rv2848c Rv2849c: Rv2849c - Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity), at 3,157,521 to 3,158,144 Rv2849c Rv2850c: Rv2850c - Possible magnesium chelatase, at 3,158,165 to 3,160,054 Rv2850c
Group Condition Rv2846c Rv2847c Rv2848c Rv2849c Rv2850c
carbon source cholesterol 100uM (C) N.D. N.D. -0.7 -0.8 -2.2
stress 7H9 with nitrite 1.5 mM; pH 5.5 N.D. N.D. -0.3 -0.0 -3.3
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. N.D. -0.4 -0.2 -1.7
carbon source heptadecanoic 250 uM (C) N.D. N.D. -0.4 -0.2 -1.7
carbon source butyrate 10 mM (C) N.D. N.D. +0.0 -0.2 -1.8
carbon source cholesterol 100uM (C) N.D. N.D. -0.6 -0.0 -1.4
no stress control no stress control N.D. N.D. -0.5 +0.1 -1.5
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM N.D. N.D. -0.3 -0.4 -1.1
stress 7H9 with Nickel (II) chloride 0.6 mM N.D. N.D. -0.0 -0.5 -1.2
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM N.D. N.D. +0.0 -0.4 -1.3
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM N.D. N.D. -0.3 -0.1 -1.2
stress 7H9 with hypochlorite 0.4 vol% N.D. N.D. -0.4 +0.0 -1.1
stress 7H9 with hypochlorite 0.4 vol% N.D. N.D. +0.4 -0.2 -0.9
nitrogen source Ammonium chloride 10mM (N) N.D. N.D. -0.6 -0.5 +0.8
stress 7H9 with Amikacin di2 ug/mL N.D. N.D. -0.6 +0.7 -0.3
stress 7H9 with Sisomicin 0.07 mM N.D. N.D. +0.9 +0.4 -1.4
carbon source oleate 200uM (C) N.D. N.D. -0.4 -0.3 +1.0
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 N.D. N.D. -0.3 -0.3 +1.1
stress 7H9 with Benzethonium chloride 0.068 mM N.D. N.D. -0.1 -0.4 +1.2
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 N.D. N.D. -0.4 +0.2 +1.4
stress 7H9 with Doxycycline hyclate 0.0035 mM N.D. N.D. -0.3 -0.1 +1.5
stress 7H9 with Formaldehyde 0.23 mM N.D. N.D. +0.0 -0.3 +1.6
stress 7H9 with Hydrogen peroxide 3.97 mM N.D. N.D. -0.4 +0.2 +1.6
carbon source D-Trehalose 10 mM (C) N.D. N.D. +0.3 +0.4 +1.0
stress 7H9 with Menadione 0.005 mM N.D. N.D. +0.3 +0.4 +1.1
stress 7H9 with Plumbagin 0.01 mM N.D. N.D. +0.4 +0.3 +1.2
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM N.D. N.D. +0.5 +0.5 +0.9
stress 7H9 with Irgasan 0.065 mM N.D. N.D. +0.1 +0.5 +1.9
no stress control no stress control N.D. N.D. +0.6 +0.3 +1.7
stress 7H9 with Linezolid 0.3 ug/mL N.D. N.D. +0.5 +0.7 +1.6
remove
Rv2846c
plot		 remove
Rv2847c
plot		 remove
Rv2848c		 remove
Rv2849c
plot		 remove
Rv2850c
plot