Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

Add gene:

Number of genes on each side:  

Top 30 experiments (either direction), sorted by average fitness

Or view all 101 experiments or choose conditions or try the comparative fitness browser

500 ntRv2845c and Rv2846c are separated by 88 nucleotidesRv2846c and Rv2847c are separated by 22 nucleotidesRv2847c and Rv2848c are separated by 276 nucleotidesRv2848c and Rv2849c overlap by 1 nucleotides Rv2845c: Rv2845c - Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase), at 3,151,202 to 3,152,950 Rv2845c Rv2846c: Rv2846c - Possible integral membrane efflux protein EfpA, at 3,153,039 to 3,154,631 Rv2846c Rv2847c: Rv2847c - Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase, at 3,154,654 to 3,155,871 Rv2847c Rv2848c: Rv2848c - Probable cobyrinic acid A,C-diamide synthase CobB, at 3,156,148 to 3,157,521 Rv2848c Rv2849c: Rv2849c - Probable cob(I)alamin adenosyltransferase CobO (corrinoid adenosyltransferase) (corrinoid adotransferase activity), at 3,157,521 to 3,158,144 Rv2849c
Group Condition Rv2845c Rv2846c Rv2847c Rv2848c Rv2849c
nitrogen source L-Aspartic Acid 10 mM (N) N.D. N.D. N.D. -0.2 -0.7
nitrogen source L-Valine 10 mM (N) N.D. N.D. N.D. -0.3 -0.4
stress 7H9 with Clarithromycin 0.967 ug/mL N.D. N.D. N.D. -0.7 +0.1
no stress control no stress control N.D. N.D. N.D. -0.3 -0.3
carbon source heptadecanoic 250 uM (C) N.D. N.D. N.D. -0.4 -0.2
stress 7H9 with Delamanid 0.236 ug/mL N.D. N.D. N.D. -0.3 -0.3
carbon source Stearic 100 uM (C) N.D. N.D. N.D. -0.1 -0.5
stress 7H9 with Ethambutol 0.75 ug/mL N.D. N.D. N.D. -0.5 +0.1
nitrogen source L-Valine 10 mM (N) N.D. N.D. N.D. +0.1 -0.5
stress 7H9 with para-aminosalicylic 0.086 ug/mL N.D. N.D. N.D. +0.2 -0.5
no stress control no stress control N.D. N.D. N.D. -0.5 +0.4
stress 7H9 with Bedaquiline 0.15 ug/mL N.D. N.D. N.D. -0.4 +0.4
stress 7H9 with Rifampicin 0.014 ug/mL N.D. N.D. N.D. -0.3 +0.4
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. N.D. N.D. -0.3 +0.4
carbon source L-Glutamine (C) N.D. N.D. N.D. +0.5 -0.2
carbon source L-Lactate 10 mM (C) N.D. N.D. N.D. +0.4 -0.2
carbon source Glycerol (C) N.D. N.D. N.D. +0.5 -0.1
carbon source Palmitic 100 uM (C) N.D. N.D. N.D. -0.1 +0.5
stress 7H9 with Rifampicin 0.014 ug/mL N.D. N.D. N.D. -0.1 +0.5
carbon source L-Aspartic Acid (C) N.D. N.D. N.D. +0.5 -0.1
stress 7H9 with Bedaquiline 0.15 ug/mL N.D. N.D. N.D. -0.0 +0.5
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. N.D. +0.1 +0.4
carbon source L-Aspartic Acid (C) N.D. N.D. N.D. +0.6 -0.0
stress 7H9 with Hygromycin B 0.0095 mM N.D. N.D. N.D. +0.2 +0.3
carbon source L-Asparagine (C) N.D. N.D. N.D. +0.4 +0.1
carbon source D-Glucose (C) N.D. N.D. N.D. +0.2 +0.4
carbon source D-Trehalose 10 mM (C) N.D. N.D. N.D. +0.3 +0.3
stress 7H9 with Clofazimine 0.072 ug/mL N.D. N.D. N.D. +0.1 +0.5
carbon source pyruvate (C) N.D. N.D. N.D. +0.5 +0.2
carbon source D-Trehalose 10 mM (C) N.D. N.D. N.D. +0.3 +0.5
remove
Rv2845c
plot		 remove
Rv2846c
plot		 remove
Rv2847c		 remove
Rv2848c
plot		 remove
Rv2849c
plot