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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2833c and Rv2834c are separated by 2 nucleotides
Rv2834c and Rv2835c overlap by 4 nucleotides
Rv2835c and Rv2836c are separated by 86 nucleotides
Rv2836c and Rv2837c are separated by 6 nucleotides
Rv2833c: Rv2833c - Probable Sn-glycerol-3-phosphate-binding lipoprotein UgpB, at 3,139,174 to 3,140,484
Rv2833c
Rv2834c: Rv2834c - Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpE, at 3,140,487 to 3,141,314
Rv2834c
Rv2835c: Rv2835c - Probable Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter UgpA, at 3,141,311 to 3,142,222
Rv2835c
Rv2836c: Rv2836c - Possible DNA-damage-inducible protein F DinF, at 3,142,309 to 3,143,628
Rv2836c
Rv2837c: Rv2837c - Conserved protein, at 3,143,635 to 3,144,645
Rv2837c
Group
Condition
Rv2833c
Rv2834c
Rv2835c
Rv2836c
Rv2837c
no stress control
no stress control
N.D.
-0.6
-0.5
-1.0
N.D.
no stress control
no stress control
N.D.
-0.7
-0.3
-1.1
N.D.
stress
7H9 with Bedaquiline 0.15 ug/mL
N.D.
-0.5
-0.5
-0.9
N.D.
stress
7H9 with Isoniazid 0.025 ug/mL
N.D.
-0.4
-0.2
-0.8
N.D.
stress
7H9 with Rifampicin 0.00045 ug/mL
N.D.
-0.5
-0.3
-0.5
N.D.
stress
7H9 with Ramoplanin 0.009 mM
N.D.
+0.1
-0.5
-0.8
N.D.
stress
7H9 with Rifampicin 0.014 ug/mL
N.D.
-0.4
-0.4
-0.4
N.D.
stress
7H9 with Econazole nitrate salt 0.0082 mM
N.D.
-0.3
-0.4
-0.5
N.D.
stress
7H9 with Menadione 0.005 mM
N.D.
+0.4
-0.3
-1.0
N.D.
stress
7H9 with Levofloxacin 0.3 ug/mL
N.D.
-0.4
+0.2
-0.7
N.D.
stress
7H9 with Antimycin A 0.0186 mM
N.D.
-0.1
+0.2
-0.9
N.D.
stress
7H9 with Ciprofloxacin Hydrochloride 0.0012 mM
N.D.
+0.3
-0.3
-0.7
N.D.
stress
7H9 with Geneticin G418 0.35 mM
N.D.
+0.2
-0.5
-0.4
N.D.
carbon source
acetate (C)
N.D.
+0.2
+0.1
-0.8
N.D.
stress
7H9 with Moxifloxacin 0.121 ug/mL
N.D.
-0.4
-0.5
+0.3
N.D.
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
N.D.
-0.5
-0.4
+0.3
N.D.
stress
7H9 with nitrate 4 mM
N.D.
-0.7
-0.5
+0.8
N.D.
stress
7H9 with nitrite 1.5 mM; pH 5.5
N.D.
+0.3
+0.2
-0.6
N.D.
stress
7H9 with Geneticin G418 0.35 mM
N.D.
-0.2
-0.4
+0.5
N.D.
carbon source
oleate 200uM (C)
N.D.
-0.5
-0.1
+0.7
N.D.
carbon source
pyruvate (C)
N.D.
+0.3
-0.5
+0.3
N.D.
stress
7H9 with Chlorpromazine 0.054 mM
N.D.
+0.0
-0.4
+0.6
N.D.
stress
7H9 with Spectinomycin 0.029 mM
N.D.
-0.5
+0.3
+0.5
N.D.
nitrogen source
Glycine 10 mM (N)
N.D.
-0.4
+0.5
+0.4
N.D.
stress
7H9 with Tetracycline 0.0058 mM
N.D.
+0.2
-0.2
+0.9
N.D.
stress
7H9 with Cloxacillin 0.0386 mM
N.D.
+0.5
-0.2
+0.6
N.D.
stress
7H9 with Benzethonium chloride 0.068 mM
N.D.
+0.2
-0.2
+1.0
N.D.
pH
7H9 pH 5.5
N.D.
+0.7
-0.1
+0.4
N.D.
stress
7H9 with Chlorhexidine diacetate salt 0.0021 mM
N.D.
+0.4
+0.0
+0.9
N.D.
stress
7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
N.D.
+0.3
+0.3
+1.0
N.D.
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