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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2706c and Rv2707 are separated by 115 nucleotides
Rv2707 and Rv2708c are separated by 0 nucleotides
Rv2708c and Rv2709 are separated by 42 nucleotides
Rv2709 and Rv2710 are separated by 175 nucleotides
Rv2706c: Rv2706c - Hypothetical protein, at 3,020,200 to 3,020,457
Rv2706c
Rv2707: Rv2707 - Probable conserved transmembrane alanine and leucine rich protein, at 3,020,573 to 3,021,547
Rv2707
Rv2708c: Rv2708c - Conserved hypothetical protein, at 3,021,548 to 3,021,796
Rv2708c
Rv2709: Rv2709 - Probable conserved transmembrane protein, at 3,021,839 to 3,022,285
Rv2709
Rv2710: Rv2710 - RNA polymerase sigma factor SigB, at 3,022,461 to 3,023,432
Rv2710
Group
Condition
Rv2706c
Rv2707
Rv2708c
Rv2709
Rv2710
stress
7H9 with Ethionamide 0.1 ug/mL
-0.0
-1.8
-1.2
-1.4
N.D.
stress
7H9 with Isoniazid 0.025 ug/mL
-0.6
-1.5
-1.2
-0.8
N.D.
no stress control
no stress control
-0.7
-1.2
-0.0
-1.0
N.D.
stress
7H9 with Isoniazid 0.025 ug/mL
+0.8
-1.8
-0.6
-1.2
N.D.
stress
7H9 with Hygromycin B 0.0095 mM
-0.7
-1.0
-0.3
-0.7
N.D.
stress
7H9 with Ethionamide 0.1 ug/mL
+0.4
-1.7
-0.5
-1.0
N.D.
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.7
-1.0
-0.0
-0.9
N.D.
stress
7H9 with Streptomycin 0.178 ug/mL
-0.9
-1.0
+0.2
-0.9
N.D.
no stress control
no stress control
-0.6
-1.2
+0.3
-1.0
N.D.
carbon source
pyruvate (C)
-1.2
-0.6
-0.0
-0.5
N.D.
nitrogen source
Glycine 10 mM (N)
-0.6
-1.1
-0.7
+0.0
N.D.
nitrogen source
L-Asparagine 10 mM (N)
-0.7
-1.0
-0.3
-0.1
N.D.
stress
7H9 with Meropenem 9.6 ug/mL
-1.1
-1.2
+0.4
-0.2
N.D.
carbon source
L-Asparagine (C)
-0.8
-1.4
+0.3
-0.0
N.D.
no stress control
no stress control
-0.8
-0.7
+0.3
-0.7
N.D.
stress
7H9 with Streptomycin 0.178 ug/mL
-0.5
-1.0
+0.4
-0.8
N.D.
carbon source
L-Glutamine (C)
-0.7
-0.8
+0.1
-0.4
N.D.
stress
7H9 with Hygromycin B 0.0095 mM
+0.2
-1.1
-0.0
-0.9
N.D.
carbon source
L-Asparagine (C)
-0.9
-1.2
+0.1
+0.1
N.D.
carbon source
D,L-Malic Acid 10 mM (C)
-1.2
-0.7
+0.2
-0.1
N.D.
stress
7H9 with Dimethyl Sulfoxide 1 vol%
-0.3
-1.0
+0.8
-1.2
N.D.
no stress control
no stress control
-0.3
-1.0
+0.8
-1.1
N.D.
stress
7H9 with Delamanid 0.236 ug/mL
-0.7
-0.6
+0.4
-0.6
N.D.
carbon source
Valeric 10 mM (C)
+0.3
-0.7
-0.1
-1.0
N.D.
no stress control
no stress control
+0.3
-1.0
+0.2
-0.9
N.D.
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.8
-0.5
-0.6
+0.4
N.D.
stress
7H9 with Levofloxacin 0.3 ug/mL
+0.6
-0.4
+1.0
-0.5
N.D.
stress
7H9 with Moxifloxacin 0.121 ug/mL
+1.7
-0.1
-0.0
+0.5
N.D.
stress
7H9 with Rifampicin 0.014 ug/mL
+0.5
+0.7
+0.1
+1.1
N.D.
stress
7H9 with Rifampicin 0.014 ug/mL
+0.7
+0.7
+0.5
+1.0
N.D.
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