Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2695 and Rv2696c are separated by 205 nucleotidesRv2696c and Rv2697c are separated by 74 nucleotidesRv2697c and Rv2698 are separated by 25 nucleotidesRv2698 and Rv2699c are separated by 4 nucleotides Rv2695: Rv2695 - Conserved hypothetical alanine rich protein, at 3,011,916 to 3,012,623 Rv2695 Rv2696c: Rv2696c - Conserved alanine and glycine and valine rich protein, at 3,012,829 to 3,013,608 Rv2696c Rv2697c: Rv2697c - Probable deoxyuridine 5'-triphosphate nucleotidohydrolase Dut (dUTPase) (dUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (dUTP diphosphatase) (deoxyuridine-triphosphatase), at 3,013,683 to 3,014,147 Rv2697c Rv2698: Rv2698 - Probable conserved alanine rich transmembrane protein, at 3,014,173 to 3,014,658 Rv2698 Rv2699c: Rv2699c - Conserved hypothetical protein, at 3,014,663 to 3,014,965 Rv2699c
Group Condition Rv2695 Rv2696c Rv2697c Rv2698 Rv2699c
stress 7H9 with Bedaquiline 0.15 ug/mL -0.2 -2.7 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.45 ug/mL -0.2 -2.5 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.072 ug/mL -0.4 -1.9 N.D. N.D. N.D.
carbon source Stearic 100 uM (C) -0.0 -2.1 N.D. N.D. N.D.
stress 7H9 with Bedaquiline 0.15 ug/mL +0.0 -2.2 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.45 ug/mL -0.1 -1.7 N.D. N.D. N.D.
stress 7H9 with Delamanid 0.236 ug/mL -0.4 -1.3 N.D. N.D. N.D.
carbon source L-Asparagine (C) -0.4 -1.1 N.D. N.D. N.D.
carbon source L-Glutamine (C) -0.1 -1.3 N.D. N.D. N.D.
stress 7H9 with Sulfamethizole 0.026 mM -0.6 -0.7 N.D. N.D. N.D.
stress 7H9 with Clofazimine 0.072 ug/mL -0.0 -1.3 N.D. N.D. N.D.
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 -1.1 N.D. N.D. N.D.
nitrogen source Glycine 10 mM (N) -0.1 -1.0 N.D. N.D. N.D.
nitrogen source L-Asparagine 10 mM (N) -0.2 -0.8 N.D. N.D. N.D.
carbon source Glycerol (C) +0.1 -1.0 N.D. N.D. N.D.
carbon source L-Asparagine (C) -0.3 -0.7 N.D. N.D. N.D.
nitrogen source L-Aspartic Acid 10 mM (N) -0.2 -0.7 N.D. N.D. N.D.
nitrogen source L-Glutamine 10 mM (N) -0.1 -0.7 N.D. N.D. N.D.
stress 7H9 with Meropenem 9.6 ug/mL -0.2 -0.7 N.D. N.D. N.D.
carbon source Stearic 100 uM (C) -0.1 -0.7 N.D. N.D. N.D.
nitrogen source L-Asparagine 10 mM (N) -0.1 -0.7 N.D. N.D. N.D.
stress 7H9 with Ethambutol 0.75 ug/mL +0.1 -0.9 N.D. N.D. N.D.
stress 7H9 with Clarithromycin 0.967 ug/mL +0.1 -0.8 N.D. N.D. N.D.
carbon source propionate (C) +0.1 -0.8 N.D. N.D. N.D.
carbon source D-Lactate 10 mM (C) +0.5 -0.4 N.D. N.D. N.D.
stress 7H9 with Isoniazid 0.025 ug/mL +0.9 -0.6 N.D. N.D. N.D.
stress 7H9 with Sulfaquinoxaline 0.097 mM -0.3 +1.0 N.D. N.D. N.D.
no stress control no stress control +0.1 +0.7 N.D. N.D. N.D.
carbon source Palmitic 100 uM (C) +0.3 +0.6 N.D. N.D. N.D.
carbon source D-Lactate 10 mM (C) +0.5 +0.9 N.D. N.D. N.D.
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