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Cofit
Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2691 and Rv2692 overlap by 4 nucleotides
Rv2692 and Rv2693c are separated by 10 nucleotides
Rv2693c and Rv2694c are separated by 30 nucleotides
Rv2694c and Rv2695 are separated by 148 nucleotides
Rv2691: Rv2691 - TRK system potassium uptake protein CeoB, at 3,009,344 to 3,010,027
Rv2691
Rv2692: Rv2692 - TRK system potassium uptake protein CeoC, at 3,010,024 to 3,010,686
Rv2692
Rv2693c: Rv2693c - Probable conserved integral membrane alanine and leucine rich protein, at 3,010,697 to 3,011,368
Rv2693c
Rv2694c: Rv2694c - Conserved protein, at 3,011,399 to 3,011,767
Rv2694c
Rv2695: Rv2695 - Conserved hypothetical alanine rich protein, at 3,011,916 to 3,012,623
Rv2695
Group
Condition
Rv2691
Rv2692
Rv2693c
Rv2694c
Rv2695
stress
7H9 with Clofazimine 0.45 ug/mL
-1.9
N.D.
-0.8
-1.9
-0.1
stress
7H9 with Delamanid 0.236 ug/mL
-1.5
N.D.
-0.4
-2.3
-0.4
stress
7H9 with Clofazimine 0.072 ug/mL
-1.6
N.D.
-0.4
-1.9
-0.4
stress
7H9 with Clofazimine 0.45 ug/mL
-1.8
N.D.
-0.8
-1.6
-0.2
stress
7H9 with Meropenem 9.6 ug/mL
-1.6
N.D.
-0.4
-1.9
+0.1
stress
7H9 with Meropenem 9.6 ug/mL
-1.4
N.D.
-0.5
-1.8
-0.2
carbon source
Glycerol (C)
-1.7
N.D.
-0.4
-1.6
-0.2
stress
7H9 with Clarithromycin 0.967 ug/mL
-1.2
N.D.
-0.6
-1.9
+0.0
stress
7H9 with Sulfamethizole 0.026 mM
-1.1
N.D.
-0.2
-1.7
-0.6
carbon source
Glycerol (C)
-1.7
N.D.
-0.3
-1.6
+0.1
stress
7H9 with Clarithromycin 0.967 ug/mL
-1.5
N.D.
-0.5
-1.6
+0.1
carbon source
L-Asparagine (C)
-1.7
N.D.
-0.1
-1.2
-0.4
nitrogen source
L-Asparagine 10 mM (N)
-1.2
N.D.
-0.1
-1.8
-0.2
stress
7H9 with Streptomycin 0.178 ug/mL
-1.5
N.D.
-0.2
-1.4
-0.2
carbon source
L-Asparagine (C)
-1.3
N.D.
-0.5
-1.3
-0.3
stress
7H9 with Streptomycin 0.178 ug/mL
-1.1
N.D.
-0.3
-1.7
-0.1
stress
7H9 with Delamanid 0.236 ug/mL
-1.1
N.D.
-0.5
-1.6
+0.0
stress
7H9 with Hygromycin B 0.0095 mM
-1.2
N.D.
-0.5
-1.2
-0.2
carbon source
heptadecanoic 250 uM (C)
-1.1
N.D.
-0.4
-1.6
-0.1
carbon source
L-Glutamine (C)
-1.2
N.D.
-0.3
-1.1
-0.3
stress
7H9 with Ethionamide 0.1 ug/mL
-1.7
N.D.
+0.0
-1.5
+0.3
carbon source
Stearic 100 uM (C)
-0.9
N.D.
-0.2
-1.7
-0.0
no stress control
no stress control
-0.8
N.D.
-0.4
-1.4
-0.2
stress
7H9 with Rifampicin 0.014 ug/mL
-0.6
N.D.
-1.0
-0.9
-0.3
carbon source
heptadecanoic 250 uM (C)
-1.0
N.D.
-0.4
-1.3
-0.1
carbon source
L-Glutamine (C)
-0.9
N.D.
-0.5
-1.1
-0.1
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.9
N.D.
+0.1
-1.7
-0.2
stress
7H9 with Rifampicin 0.00045 ug/mL
-0.7
N.D.
-0.9
-1.0
-0.1
stress
7H9 with Hygromycin B 0.0095 mM
-1.4
N.D.
-0.2
-1.1
+0.5
stress
7H9 with Ethionamide 0.1 ug/mL
-1.0
N.D.
+0.3
-1.6
+0.4
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