Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2691 and Rv2692 overlap by 4 nucleotidesRv2692 and Rv2693c are separated by 10 nucleotidesRv2693c and Rv2694c are separated by 30 nucleotidesRv2694c and Rv2695 are separated by 148 nucleotides Rv2691: Rv2691 - TRK system potassium uptake protein CeoB, at 3,009,344 to 3,010,027 Rv2691 Rv2692: Rv2692 - TRK system potassium uptake protein CeoC, at 3,010,024 to 3,010,686 Rv2692 Rv2693c: Rv2693c - Probable conserved integral membrane alanine and leucine rich protein, at 3,010,697 to 3,011,368 Rv2693c Rv2694c: Rv2694c - Conserved protein, at 3,011,399 to 3,011,767 Rv2694c Rv2695: Rv2695 - Conserved hypothetical alanine rich protein, at 3,011,916 to 3,012,623 Rv2695
Group Condition Rv2691 Rv2692 Rv2693c Rv2694c Rv2695
pH pH 4.5 -3.0 N.D. -1.8 -2.7 -0.7
pH pH 4.5 -2.3 N.D. -1.0 -3.6 -0.4
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -1.7 N.D. -0.5 -2.9 -0.9
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -2.0 N.D. -0.2 -2.2 -1.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -2.1 N.D. -0.5 -2.7 +0.0
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.8 N.D. -0.5 -2.2 -0.8
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -1.5 N.D. -0.4 -2.5 -0.7
stress 7H9 with Cumene hydroperoxide 0.05 mM -1.8 N.D. -0.6 -2.3 -0.4
stress 7H9 with methylglyoxal 1.2 mM -2.0 N.D. -0.3 -2.2 -0.5
stress 7H9 with Hydrogen peroxide 3.97 mM -2.3 N.D. -0.5 -1.6 -0.3
stress 7H9 with Clofazimine 0.45 ug/mL -1.9 N.D. -0.8 -1.9 -0.1
stress 7H9 with Delamanid 0.236 ug/mL -1.5 N.D. -0.5 -2.3 -0.4
stress 7H9 with Clofazimine 0.072 ug/mL -1.6 N.D. -0.4 -1.9 -0.4
stress 7H9 with Cumene hydroperoxide 0.05 mM -1.6 N.D. -0.6 -2.1 -0.1
stress 7H9 with Clofazimine 0.45 ug/mL -1.8 N.D. -0.8 -1.6 -0.2
stress 7H9 with methylglyoxal 1.2 mM -1.8 N.D. -0.2 -2.0 -0.1
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM -1.4 N.D. -0.6 -2.1 -0.2
stress 7H9 with Meropenem 9.6 ug/mL -1.4 N.D. -0.5 -1.8 -0.2
stress 7H9 with Meropenem 9.6 ug/mL -1.6 N.D. -0.4 -1.9 +0.1
stress 7H9 with Clarithromycin 0.967 ug/mL -1.2 N.D. -0.6 -2.0 +0.0
carbon source Glycerol (C) -1.7 N.D. -0.4 -1.6 -0.2
stress 7H9 with nitrite 3 mM; pH 5.5 -1.5 N.D. -0.4 -1.8 -0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -1.7 N.D. -0.3 -1.6 -0.1
stress 7H9 with Benzethonium chloride 0.068 mM -1.4 N.D. -0.7 -1.5 -0.2
stress 7H9 with nitrate 4 mM -1.2 N.D. -0.5 -1.8 -0.1
stress 7H9 with Sulfamethizole 0.026 mM -1.1 N.D. -0.2 -1.7 -0.6
stress 7H9 with Clarithromycin 0.967 ug/mL -1.5 N.D. -0.5 -1.6 +0.0
carbon source Glycerol (C) -1.7 N.D. -0.3 -1.6 +0.1
stress 7H9 with Antimycin A 0.0186 mM -1.3 N.D. +0.4 -2.0 +0.1
stress 7H9 with nitrite 1.5 mM; pH 5.5 -1.8 N.D. +0.4 -1.5 +0.2
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