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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv2658c and Rv2659c are separated by 2 nucleotides
Rv2659c and Rv2660c are separated by 144 nucleotides
Rv2660c and Rv2661c overlap by 4 nucleotides
Rv2661c and Rv2662 overlap by 95 nucleotides
Rv2658c: Rv2658c - Possible prophage protein, at 2,979,326 to 2,979,688
Rv2658c
Rv2659c: Rv2659c - Probable PhiRv2 prophage integrase, at 2,979,691 to 2,980,818
Rv2659c
Rv2660c: Rv2660c - Hypothetical protein, at 2,980,963 to 2,981,190
Rv2660c
Rv2661c: Rv2661c - Hypothetical protein, at 2,981,187 to 2,981,576
Rv2661c
Rv2662: Rv2662 - Hypothetical protein, at 2,981,482 to 2,981,754
Rv2662
Group
Condition
Rv2658c
Rv2659c
Rv2660c
Rv2661c
Rv2662
stress
7H9 with Dibucaine 0.21 mM
+0.1
-0.0
+0.0
-1.9
-0.2
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
-0.1
+0.0
-0.8
-0.7
-0.4
stress
7H9 with 8-hydroxy-nitroquinoline 0.03 mM
+0.0
+0.0
+0.2
-1.9
+0.2
stress
7H9 with nitrite 5 mM
+0.2
+0.1
+0.0
-1.2
-0.4
stress
7H9 with Chlorhexidine diacetate salt 0.0021 mM
-0.0
-0.1
+0.6
-1.3
+0.1
pH
pH 5.5
-0.2
+0.3
+0.2
-1.1
+0.2
stress
7H9 with Phenazine ethosulfate 0.0137 mM
-0.3
+0.1
-1.0
+0.8
-0.3
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 6.5
-0.0
+0.1
+0.2
-0.9
+0.6
stress
7H9 with Isoniazid 0.025 ug/mL
-0.3
-0.2
+0.3
-0.7
+1.0
stress
7H9 with 2,4-Dinitrophenol 0.1503 mM
+0.2
-0.0
-0.5
+0.8
-0.3
no stress control
no stress control
-0.1
+0.3
+0.2
-0.9
+0.8
stress
7H9 with Cloxacillin 0.0386 mM
-0.2
+0.4
+0.2
+0.7
-0.7
stress
7H9 with Hydrogen peroxide 2.5 mM; pH 5.5
+0.0
+0.4
+0.5
-0.7
+0.5
stress
7H9 with Novobiocin 0.004 mM
+0.1
+0.1
+0.3
+1.0
-0.6
stress
7H9 with Econazole nitrate salt 0.0082 mM
-0.2
-0.0
-0.4
+1.1
+0.3
stress
7H9 with Moxifloxacin 0.121 ug/mL
-0.3
+0.4
+0.5
-0.4
+0.6
pH
pH 4.5
+0.3
-0.1
+0.2
+0.8
-0.4
stress
7H9 with Novobiocin 0.004 mM
+0.0
+0.0
+0.3
+1.3
-0.5
no stress control
no stress control
+0.1
+0.3
+0.6
+0.7
-0.5
stress
7H9 with Hydrogen peroxide 3.97 mM
-0.0
+0.1
-0.5
+0.9
+0.7
stress
7H9 with Ofloxacin 0.8 ug/mL
-0.2
-0.1
+0.4
+0.0
+1.2
stress
7H9 with Lomefloxacin 0.0035 mM
-0.2
+0.2
+0.1
+1.3
+0.2
stress
7H9 with Delamanid 0.236 ug/mL
-0.1
-0.0
+0.1
+1.1
+0.6
stress
7H9 with Irgasan 0.065 mM
-0.1
+0.3
+0.1
+1.4
-0.1
stress
7H9 with Dimethyl Sulfoxide 1 vol%
+0.0
-0.2
+0.3
+0.8
+0.6
no stress control
no stress control
+0.1
-0.1
+0.1
+1.1
+0.5
stress
7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM
+0.0
+0.2
+0.6
+1.1
-0.0
stress
7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM
+0.1
+0.1
+0.3
+1.1
+0.5
stress
7H9 with Dodecyl Sulfate 0.02 vol%
-0.0
+0.2
+0.2
+1.3
+0.4
stress
7H9 with Menadione 0.005 mM
-0.2
+0.1
+0.1
+2.2
-0.0
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