Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2631 and Rv2632c are separated by 38 nucleotidesRv2632c and Rv2633c are separated by 144 nucleotidesRv2633c and Rv2634c are separated by 284 nucleotidesRv2634c and Rv2635 are separated by 28 nucleotides Rv2631: Rv2631 - Conserved hypothetical protein, at 2,957,572 to 2,958,870 Rv2631 Rv2632c: Rv2632c - Conserved protein, at 2,958,909 to 2,959,190 Rv2632c Rv2633c: Rv2633c - Hypothetical protein, at 2,959,335 to 2,959,820 Rv2633c Rv2634c: Rv2634c - PE-PGRS family protein PE_PGRS46, at 2,960,105 to 2,962,441 Rv2634c Rv2635: Rv2635 - Hypothetical protein, at 2,962,470 to 2,962,712 Rv2635
Group Condition Rv2631 Rv2632c Rv2633c Rv2634c Rv2635
carbon source oleate 200uM (C) -0.0 -0.8 +0.5 -0.2 -4.0
pH pH 4.5 -0.1 -1.1 -0.9 -0.2 -1.8
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 -0.2 -0.6 -0.1 -2.4
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.1 +0.2 -0.3 -0.2 -2.4
stress 7H9 with Irgasan 0.065 mM -0.1 -0.7 -0.3 +0.2 -1.5
stress 7H9 with Sisomicin 0.07 mM -0.3 +0.3 +0.4 -0.1 -1.8
stress 7H9 with Zinc Pyrithione 0.00072 mM +0.0 -2.6 +0.2 +0.1 +0.9
nitrogen source Ammonium chloride 10mM (N) +0.3 -0.2 +0.2 +0.2 -1.6
nitrogen source Urea 10mM (N) +0.4 -0.9 +0.3 +0.1 -0.9
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +0.3 +0.1 +0.7 +0.2 -2.2
no stress control no stress control +0.2 +0.5 +0.1 +0.2 -1.7
carbon source Palmitic 100 uM (C) -0.2 +0.5 +0.6 -0.1 -1.4
carbon source Palmitic 100 uM (C) +0.0 +1.0 +0.7 -0.1 -1.9
nitrogen source L-Glutamic 10 mM (N) +0.3 -1.1 +1.1 -0.1 -0.6
stress 7H9 with Cloxacillin 0.0386 mM +0.2 +0.4 +0.7 -0.0 -1.4
carbon source propionate (C) +0.2 +0.9 -0.1 +0.1 -1.3
stress 7H9 with Norfloxacin 0.125 mM +0.1 +0.4 +0.9 -0.1 -1.2
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.3 +0.3 +0.9 -0.1 -1.2
stress 7H9 with Levofloxacin 0.3 ug/mL +0.1 -1.0 +1.0 +0.1 +0.7
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.0 +0.9 +1.0 +0.0 -1.0
stress 7H9 with Spectinomycin 0.029 mM -0.1 +1.7 +0.5 +0.0 -0.9
stress 7H9 with Isoniazid 0.025 ug/mL -0.2 +0.8 -0.5 -0.2 +1.7
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.1 +1.3 +1.3 -0.1 -0.8
stress 7H9 with Geneticin G418 0.35 mM +0.4 -0.5 +0.9 +0.1 +0.7
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.1 -0.5 +1.2 -0.1 +1.3
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 -0.2 +1.2 -0.1 +1.3
stress 7H9 with Lomefloxacin 0.0035 mM +0.1 +0.9 +1.1 -0.1 +0.4
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.1 +1.4 +1.2 +0.1 -0.2
pH 7H9 pH 5.5 +0.3 +1.5 +0.6 +0.2 +0.1
stress 7H9 with Benzethonium chloride 0.068 mM +0.2 +1.6 +0.6 +0.1 +0.3
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