Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2568c and Rv2569c overlap by 8 nucleotidesRv2569c and Rv2570 are separated by 103 nucleotidesRv2570 and Rv2571c overlap by 9 nucleotidesRv2571c and Rv2572c are separated by 52 nucleotides Rv2568c: Rv2568c - Conserved hypothetical protein, at 2,892,446 to 2,893,471 Rv2568c Rv2569c: Rv2569c - Conserved hypothetical protein, at 2,893,464 to 2,894,408 Rv2569c Rv2570: Rv2570 - Conserved hypothetical protein, at 2,894,512 to 2,894,901 Rv2570 Rv2571c: Rv2571c - Probable transmembrane alanine and valine and leucine rich protein, at 2,894,893 to 2,895,960 Rv2571c Rv2572c: Rv2572c - Probable aspartyl-tRNA synthetase AspS (aspartate--tRNA ligase) (ASPRS) (aspartic acid translase), at 2,896,013 to 2,897,803 Rv2572c
Group Condition Rv2568c Rv2569c Rv2570 Rv2571c Rv2572c
stress 7H9 with Hygromycin B 0.0095 mM -0.3 -1.2 +0.2 -0.3 N.D.
pH 7H9 pH 5.5 +0.1 -1.1 +0.3 -0.7 N.D.
stress 7H9 with Levofloxacin 0.3 ug/mL -0.6 -0.9 -0.2 +0.5 N.D.
stress 7H9 with Nickel (II) chloride 0.6 mM +0.1 -0.8 +0.3 -0.8 N.D.
stress 7H9 with methylglyoxal 1.2 mM +0.0 -0.4 +0.5 -1.2 N.D.
no stress control no stress control -0.3 -1.1 +0.6 -0.3 N.D.
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.2 -1.1 +0.5 -0.2 N.D.
stress 7H9 with hypochlorite 0.4 vol% -0.2 -0.5 +0.9 -1.0 N.D.
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM +0.1 -0.7 +0.6 -0.5 N.D.
stress 7H9 with Formaldehyde 0.23 mM -0.4 -1.2 +0.6 +0.5 N.D.
carbon source oleate 200uM (C) -0.1 -0.2 +0.9 -1.0 N.D.
pH pH 4.5 +0.6 -0.6 +0.3 -0.6 N.D.
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.7 -0.7 +1.0 +0.1 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL +0.4 -0.8 +0.4 -0.4 N.D.
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -0.6 -0.7 +0.6 +0.4 N.D.
nitrogen source Urea 10mM (N) -0.5 -0.4 +1.2 -0.4 N.D.
no stress control no stress control +0.2 -0.8 +0.8 -0.2 N.D.
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.4 -1.0 +0.4 +0.2 N.D.
stress 7H9 with Amikacin di2 ug/mL +0.6 -1.0 +0.5 -0.1 N.D.
stress 7H9 with Dodecyl Sulfate 0.02 vol% -0.7 -0.3 +0.6 +0.6 N.D.
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.0 -0.9 +0.3 +0.9 N.D.
stress 7H9 with Geneticin G418 0.35 mM -0.3 -0.8 +1.0 +0.4 N.D.
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 +0.7 -0.9 -0.1 +0.8 N.D.
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM +0.3 -0.8 +0.7 +0.3 N.D.
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.3 -0.8 +0.6 +0.6 N.D.
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.4 -1.1 +0.3 +1.0 N.D.
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM +0.6 -0.7 +0.7 +0.1 N.D.
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.3 -0.3 +0.5 +0.9 N.D.
no stress control no stress control +0.5 -0.7 +0.9 +0.0 N.D.
stress 7H9 with Geneticin G418 0.35 mM +0.2 -0.6 +0.8 +0.4 N.D.
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