Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2553c and Rv2554c overlap by 8 nucleotidesRv2554c and Rv2555c are separated by 0 nucleotidesRv2555c and Rv2556c are separated by 90 nucleotidesRv2556c and Rv2557 are separated by 106 nucleotides Rv2553c: Rv2553c - Probable conserved membrane protein, at 2,872,012 to 2,873,265 Rv2553c Rv2554c: Rv2554c - Conserved protein, at 2,873,258 to 2,873,770 Rv2554c Rv2555c: Rv2555c - Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS), at 2,873,771 to 2,876,485 Rv2555c Rv2556c: Rv2556c - Conserved hypothetical protein, at 2,876,576 to 2,876,965 Rv2556c Rv2557: Rv2557 - Conserved protein, at 2,877,072 to 2,877,746 Rv2557
Group Condition Rv2553c Rv2554c Rv2555c Rv2556c Rv2557
nitrogen source L-Serine 10 mM (N) -3.4 N.D. N.D. -0.1 -0.2
stress 7H9 with Linezolid 0.3 ug/mL -3.4 N.D. N.D. +0.1 -0.2
no stress control no stress control -3.1 N.D. N.D. -0.3 -0.0
nitrogen source L-Asparagine 10 mM (N) -3.2 N.D. N.D. -0.1 -0.1
nitrogen source Glycine 10 mM (N) -3.3 N.D. N.D. -0.1 +0.3
stress 7H9 with Erythromycin 0.016 mM -2.9 N.D. N.D. +0.1 -0.2
stress 7H9 with Erythromycin 0.016 mM -2.9 N.D. N.D. +0.1 -0.2
nitrogen source L-Glutamine 10 mM (N) -3.0 N.D. N.D. +0.0 +0.1
nitrogen source Urea 10mM (N) -2.7 N.D. N.D. -0.1 -0.1
stress 7H9 with Rifampicin 0.00045 ug/mL -2.6 N.D. N.D. +0.0 -0.1
nitrogen source L-Aspartic Acid 10 mM (N) -2.5 N.D. N.D. -0.2 +0.1
nitrogen source Glycine 10 mM (N) -2.5 N.D. N.D. -0.0 -0.1
carbon source Glycerol (C) -2.3 N.D. N.D. -0.1 -0.1
stress 7H9 with Hydrogen peroxide 3.97 mM -2.5 N.D. N.D. +0.1 -0.2
no stress control no stress control -2.2 N.D. N.D. -0.1 -0.2
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -2.8 N.D. N.D. -0.0 +0.3
nitrogen source L-Alanine 10 mM (N) -2.5 N.D. N.D. +0.1 -0.0
nitrogen source L-Alanine 10 mM (N) -2.1 N.D. N.D. -0.1 -0.2
stress 7H9 with Tetrazolium violet 0.065 mM -1.5 N.D. N.D. -0.8 +0.0
stress 7H9 with nitrite 2.5 mM -2.2 N.D. N.D. -0.2 +0.1
stress 7H9 with Linezolid 0.3 ug/mL -2.6 N.D. N.D. +0.2 +0.1
stress 7H9 with Rifampicin 0.014 ug/mL -2.1 N.D. N.D. -0.2 +0.1
stress 7H9 with Phenazine ethosulfate 0.0137 mM -2.2 N.D. N.D. +0.0 -0.1
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -2.1 N.D. N.D. -0.2 +0.2
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM -2.4 N.D. N.D. -0.1 +0.4
carbon source butyrate 10 mM (C) -2.1 N.D. N.D. +0.1 -0.1
stress 7H9 with Tetrazolium violet 0.065 mM -1.9 N.D. N.D. +0.1 +0.3
stress 7H9 with Ofloxacin 0.8 ug/mL +1.4 N.D. N.D. -0.7 -0.2
stress 7H9 with Norfloxacin 0.125 mM +1.9 N.D. N.D. -0.3 +0.2
stress 7H9 with Ciprofloxacin Hydrochloride 0.001 mM +2.0 N.D. N.D. -0.2 +0.1
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