Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2550c and Rv2551c are separated by 410 nucleotidesRv2551c and Rv2552c are separated by 11 nucleotidesRv2552c and Rv2553c overlap by 4 nucleotidesRv2553c and Rv2554c overlap by 8 nucleotides Rv2550c: Rv2550c - Possible antitoxin VapB20, at 2,870,119 to 2,870,364 Rv2550c Rv2551c: Rv2551c - Conserved hypothetical protein, at 2,870,775 to 2,871,194 Rv2551c Rv2552c: Rv2552c - Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase), at 2,871,206 to 2,872,015 Rv2552c Rv2553c: Rv2553c - Probable conserved membrane protein, at 2,872,012 to 2,873,265 Rv2553c Rv2554c: Rv2554c - Conserved protein, at 2,873,258 to 2,873,770 Rv2554c
Group Condition Rv2550c Rv2551c Rv2552c Rv2553c Rv2554c
stress 7H9 with Linezolid 0.3 ug/mL -0.6 -1.3 N.D. -2.6 N.D.
stress 7H9 with Erythromycin 0.016 mM -0.7 -0.5 N.D. -2.9 N.D.
stress 7H9 with Erythromycin 0.016 mM -0.9 -0.1 N.D. -2.9 N.D.
stress 7H9 with Linezolid 0.3 ug/mL -0.7 +0.4 N.D. -3.4 N.D.
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 -0.9 N.D. -2.6 N.D.
nitrogen source Urea 10mM (N) +0.4 -1.2 N.D. -2.7 N.D.
nitrogen source L-Asparagine 10 mM (N) -0.0 +0.0 N.D. -3.2 N.D.
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.6 -0.4 N.D. -2.1 N.D.
stress 7H9 with Clofazimine 0.072 ug/mL -0.1 -1.1 N.D. -1.8 N.D.
nitrogen source L-Serine 10 mM (N) +0.3 +0.1 N.D. -3.4 N.D.
stress 7H9 with Hydrogen peroxide 3.97 mM -0.3 -0.2 N.D. -2.5 N.D.
nitrogen source L-Glutamine 10 mM (N) +0.3 -0.1 N.D. -3.0 N.D.
stress 7H9 with Rifampicin 0.014 ug/mL +0.2 -0.9 N.D. -2.1 N.D.
nitrogen source Glycine 10 mM (N) +0.1 +0.5 N.D. -3.3 N.D.
no stress control no stress control +0.1 +0.5 N.D. -3.1 N.D.
stress 7H9 with Phenazine ethosulfate 0.0137 mM +0.0 -0.5 N.D. -2.2 N.D.
carbon source butyrate 10 mM (C) -0.6 +0.1 N.D. -2.1 N.D.
stress 7H9 with Plumbagin 0.01 mM +0.1 -0.7 N.D. -1.9 N.D.
nitrogen source L-Alanine 10 mM (N) +0.2 -0.2 N.D. -2.5 N.D.
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.7 -0.9 N.D. -2.4 N.D.
nitrogen source Glycine 10 mM (N) +0.1 -0.1 N.D. -2.5 N.D.
nitrogen source L-Aspartic Acid 10 mM (N) +0.0 +0.3 N.D. -2.5 N.D.
carbon source Glycerol (C) +0.0 +0.2 N.D. -2.3 N.D.
no stress control no stress control -0.3 +0.5 N.D. -2.2 N.D.
nitrogen source L-Glutamic 10 mM (N) +0.6 -0.6 N.D. -2.0 N.D.
stress 7H9 with nitrite 2.5 mM -0.0 +0.4 N.D. -2.2 N.D.
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.0 +1.1 N.D. -2.8 N.D.
nitrogen source L-Alanine 10 mM (N) +0.1 +0.7 N.D. -2.1 N.D.
stress 7H9 with Tetrazolium violet 0.065 mM +0.6 +0.6 N.D. -1.9 N.D.
stress 7H9 with Sisomicin 0.07 mM -0.6 -1.2 N.D. +1.5 N.D.
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