Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv2531c and Rv2532c are separated by 71 nucleotidesRv2532c and Rv2533c overlap by 1 nucleotidesRv2533c and Rv2534c are separated by 2 nucleotidesRv2534c and Rv2535c are separated by 9 nucleotides Rv2531c: Rv2531c - Probable amino acid decarboxylase, at 2,854,938 to 2,857,781 Rv2531c Rv2532c: Rv2532c - Hypothetical protein, at 2,857,853 to 2,858,254 Rv2532c Rv2533c: Rv2533c - N utilization substance protein NusB (NusB protein), at 2,858,254 to 2,858,724 Rv2533c Rv2534c: Rv2534c - Probable elongation factor P Efp, at 2,858,727 to 2,859,290 Rv2534c Rv2535c: Rv2535c - Probable cytoplasmic peptidase PepQ, at 2,859,300 to 2,860,418 Rv2535c
Group Condition Rv2531c Rv2532c Rv2533c Rv2534c Rv2535c
nitrogen source L-Glutamine 10 mM (N) -0.1 -0.4 N.D. N.D. N.D.
stress 7H9 with Doxycycline hyclate 0.0035 mM +0.1 -0.5 N.D. N.D. N.D.
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.1 -0.5 N.D. N.D. N.D.
stress 7H9 with Chloramphenicol 0.01 mM -0.2 +0.4 N.D. N.D. N.D.
stress 7H9 with Dicloxacillin 0.0069 mM -0.1 +0.4 N.D. N.D. N.D.
stress 7H9 with hypochlorite 0.4 vol% -0.2 +0.5 N.D. N.D. N.D.
carbon source L-Lactate 10 mM (C) -0.1 +0.4 N.D. N.D. N.D.
pH 7H9 pH 5.5 -0.1 +0.5 N.D. N.D. N.D.
stress 7H9 with Novobiocin 0.004 mM -0.1 +0.5 N.D. N.D. N.D.
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 -0.1 +0.6 N.D. N.D. N.D.
stress 7H9 with Sisomicin 0.07 mM +0.1 +0.4 N.D. N.D. N.D.
no stress control no stress control +0.1 +0.5 N.D. N.D. N.D.
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.2 +0.3 N.D. N.D. N.D.
nitrogen source Ammonium chloride 10mM (N) +0.0 +0.5 N.D. N.D. N.D.
stress 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM -0.2 +0.8 N.D. N.D. N.D.
stress 7H9 with nitrite 3 mM; pH 5.5 +0.3 +0.3 N.D. N.D. N.D.
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM +0.1 +0.5 N.D. N.D. N.D.
stress 7H9 with Menadione 0.005 mM -0.1 +0.7 N.D. N.D. N.D.
stress 7H9 with Menadione 0.005 mM +0.0 +0.6 N.D. N.D. N.D.
stress 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM +0.2 +0.5 N.D. N.D. N.D.
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM +0.0 +0.6 N.D. N.D. N.D.
stress 7H9 with Cetrimonium bromide 0.015 vol% +0.0 +0.6 N.D. N.D. N.D.
stress 7H9 with copper (II) chloride 0.08 mM +0.1 +0.6 N.D. N.D. N.D.
carbon source cholesterol 100uM (C) -0.0 +0.7 N.D. N.D. N.D.
stress 7H9 with nitrite 5 mM +0.2 +0.6 N.D. N.D. N.D.
stress 7H9 with nitrite 1.5 mM; pH 5.5 +0.2 +0.5 N.D. N.D. N.D.
stress 7H9 with copper (II) chloride 0.08 mM +0.0 +0.7 N.D. N.D. N.D.
stress 7H9 with Hydrogen peroxide 3.97 mM +0.1 +0.7 N.D. N.D. N.D.
pH pH 4.5 +1.1 -0.3 N.D. N.D. N.D.
pH pH 4.5 +1.2 -0.1 N.D. N.D. N.D.
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